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16502 Kcnc1

16502

Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium voltage gated channel, Shaw-related subfamily, member 1

研究结论

Date Results Publications
2013-12-07 10:08:00 Kv3.1 channels stimulate adult neural precursor cell proliferation and neuronal differentiation. 23478135
2013-11-23 10:40:00 The resting (closed) Kv3.1 channel conformation forms the high-affinity state for gambierol. 23401573
2013-11-02 10:18:00 high-affinity multimeric binding between the Kv3.1 T1 domain and KIF5B requires three basic residues in the KIF5B tail. Kv3.1 T1 competes with the motor domain and microtubules, but not with kinesin light chain 1 (KLC1), for binding to the KIF5B tail. 23487040
2013-03-02 12:34:00 Although all Kv3 transcripts were significantly expressed at embryonic age in whole brain extracts, only Kv3.1, Kv3.2 and Kv3.4 subunit proteins were present, suggesting a novel role for Kv3 channels at this developmental stage. 21912965
2012-08-18 10:17:00 Block of Kv3.1 channels hinders spike repolarization and severely depresses evoked fast firing in deep cerebellar nuclear neurons. 21750937

名称对应

Type IDs
Synonymous C230009H10Rik, KShIIIB, KV4, Kcr2-1, Kv3.1, NGK2, Shaw
Gene
UniProtKB-ID: KCNC1_MOUSE, Q3UHB6_MOUSE, Q3TR92_MOUSE
UniprotKB: P15388, Q3UHB6, Q3TR92
UniParc: UPI000012DF17, UPI000002961D, UPI00005B1EFE
EMBL: AK162964, BC132439, Y07521, BC125470, AK147682, AK147476, AC090652, AC020786
Ensembl: ENSMUSG00000058975
KO: mmu:16502
Nucleutide sequences
EMBL-CDS: CAA68814.1, BAE28071.1, AAI32440.1, AAI25471.1, BAE27941.1, BAE37138.1
Ensembl_TRS: ENSMUST00000025202, ENSMUST00000160433
Protein sequencees
Ensembl_PRO: ENSMUSP00000124938, ENSMUSP00000025202
RefSeq: NP_001106210.1, XP_006540711.1, NP_032447.1, XP_006540709.1, XP_006540710.1
Others
UniRef100: UniRef100_Q3TR92, UniRef100_P15388
UniRef90: UniRef90_P15388
UniRef50: UniRef50_P15388
UniGene: Mm.249386
CCDS: CCDS21278.1, CCDS52252.1

全选

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