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16500 Kcnb1

16500

Kcnb1

potassium voltage gated channel, Shab-related subfamily, member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium voltage gated channel, Shab-related subfamily, member 1

研究结论

Date Results Publications
2021-03-20 13:33:00 Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvbeta1 subunit. 33060203
2020-07-11 11:44:00 Kv2.1 plays a canonical conductive role but found it also has a structural role in arterial myocytes to enhance clustering of CaV1.2 channels. 32015129
2020-06-13 11:55:00 the VAP-interacting membrane-associated phosphatidylinositol (PtdIns) transfer proteins PYK2 N-terminal domain-interacting receptor 2 (Nir2) and Nir3 specifically associate with Kv2.1 complexes. 31594866
2020-01-11 11:12:00 results suggest that Kv2.1 clusters exert a spatially discrete homeostatic braking mechanism on dopamine transporter by inducing a relative increase in inward-facing transporters 30824538
2019-10-19 11:16:00 Expression of Kv2.1 recruits VAPB and VAPA to ER-PM junctions. Knocking out VAPA expression disrupts Kv2.1 clustering.The domains of VAPs and Kv2.1 necessary and sufficient for their association at ER-PM junctions were identified. Kv2.1 expression in the plasma membrane can affect ER-PM junctions via its phosphorylation-dependent association to ER-localized VAPA and VAPB. 30012696

名称对应

Type IDs
Synonymous Kcr1-1, Kv2.1, Shab
Gene
UniProtKB-ID: KCNB1_MOUSE
UniprotKB: Q03717
UniParc: UPI0000026D26
EMBL: CH466551, BC061501, BC031776, M64228, AL591711, AL591854
Ensembl: ENSMUSG00000050556
KO: mmu:16500
Nucleutide sequences
EMBL-CDS: AAH61501.1, AAA40112.1, EDL06500.1, AAH31776.1
Ensembl_TRS: ENSMUST00000207917, ENSMUST00000059826
Protein sequencees
Ensembl_PRO: ENSMUSP00000057981, ENSMUSP00000147093
RefSeq: NP_032446.2, XP_017171221.1
Others
UniRef100: UniRef100_Q03717
UniRef90: UniRef90_P15387
UniRef50: UniRef50_P15387
UniGene: Mm.205341, Mm.490804
CCDS: CCDS17096.1

全选

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