| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel, shaker-related subfamily, member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:59:00 | Neuron-specific Kv1.1 deficiency is sufficient to cause epilepsy, premature death, and cardiorespiratory dysregulation. | 31978607 |
| 2020-10-24 14:03:00 | Progressive cardiorespiratory dysfunction in Kv1.1 knockout mice may provide temporal biomarkers of pending sudden unexpected death in epilepsy (SUDEP): The contribution of orexin. | 32030748 |
| 2020-09-12 16:00:00 | Sound Localization in Preweanling Mice Was More Severely Affected by Deleting the Kcna1 Gene Compared to Deleting Kcna2, and a Curious Inverted-U Course of Development That Appeared to Exceed Adult Performance Was Observed in All Groups. | 31410614 |
| 2020-01-11 10:44:00 | During spontaneous convulsive seizures, Kcna1(-/-) mice displayed an array of aberrant breathing patterns that always preceded cardiac abnormalities. These findings support respiratory dysfunction as a primary risk factor for susceptibility to deleterious cardiorespiratory sequelae in epilepsy and reveal a new role for Kcna1-encoded Kv1.1 channels in the regulation of basal respiratory physiology. | 30974168 |
| 2019-09-14 10:20:00 | these studies demonstrate altered Kv1.1 protein expression in association with mTOR hyperactivation in NS-Pten KO mice and suggest a role for mTOR signaling in the modulation of voltage-gated ion channel expression in this model. | 29476105 |
| Type | IDs |
|---|---|
| Synonymous | AI840627, Kca1-1, Kv1.1, MBK1, Mk-1, Shak, mceph |
| Gene |
UniProtKB-ID:
KCNA1_MOUSE
UniprotKB:
P16388
UniParc:
UPI0000020CD3
EMBL:
Y00305,
M30439
Ensembl:
ENSMUSG00000047976
KO:
mmu:16485
|
| Nucleutide sequences |
EMBL-CDS:
CAA68408.1,
AAA39711.1
Ensembl_TRS:
ENSMUST00000203094,
ENSMUST00000055168
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000144947,
ENSMUSP00000055225
RefSeq:
NP_034725.3
|
| Others |
UniRef100:
UniRef100_P16388
UniRef90:
UniRef90_Q09470
UniRef50:
UniRef50_Q09470
UniGene:
Mm.40424
CCDS:
CCDS20555.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员