| Type | Description |
|---|---|
| Definition | jumonji, AT rich interactive domain 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:14:00 | Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells. | 32181346 |
| 2020-06-27 12:28:00 | JARID2 and the PRC2 complex regulate skeletal muscle proliferation in a precise manner that involves the repression of cyclin D1, thus restraining proliferation and repressing RB1, which is required for mitotic exit and terminal differentiation | 31578284 |
| 2019-10-19 10:05:00 | This study demonstrates that ablation of Jarid2 in cardiomyocytes results in dilated cardiomyopathy and suggest that Jarid2 plays important roles in cardiomyocyte maturation during neonatal stages. | 30700554 |
| 2019-08-03 10:45:00 | In this study, genetic mouse models and patient-derived xenografts demonstrated that JARID2 acts as a tumor suppressor in chronic myeloid disorders. | 30423295 |
| 2019-02-16 10:43:00 | The deletion of Jarid2 by Nkx2.5-Cre mice (Jarid2(Nkx)) caused cardiac malformations including ventricular septal defects, thin myocardium, hypertrabeculation, and neonatal lethality. Jarid2(Nkx) mice exhibited elevated expression of neural genes, cardiac jelly, and other key factors including Isl1 and Bmp10 in the developing heart. | 29891551 |
| Type | IDs |
|---|---|
| Synonymous | Jmj, jumonji |
| Gene |
UniProtKB-ID:
JARD2_MOUSE
UniprotKB:
Q62315
UniParc:
UPI000000406B,
UPI00001E7DBF
EMBL:
CH466546,
AK147226,
D31967,
BC003374,
AK164134,
AK045214,
BC060695,
BC052444
Ensembl:
ENSMUSG00000038518
KO:
mmu:16468
|
| Nucleutide sequences |
EMBL-CDS:
AAH52444.1,
EDL41007.1,
BAE27780.1,
BAA06736.1,
AAH60695.1,
AAH03374.1,
BAC32264.1,
BAE37641.1
Ensembl_TRS:
ENSMUST00000044608,
ENSMUST00000173704,
ENSMUST00000173246
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000134205,
ENSMUSP00000037774,
ENSMUSP00000134675
RefSeq:
XP_006516923.1,
XP_036013756.1,
NP_001347210.1,
NP_001191972.1,
XP_006516921.1,
XP_006516922.1,
NP_001191973.1,
NP_068678.1,
XP_036013757.1
|
| Others |
UniRef100:
UniRef100_Q62315
UniRef90:
UniRef90_Q62315
UniRef50:
UniRef50_Q62315
UniGene:
Mm.25059
CCDS:
CCDS36646.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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