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1646 AKR1C2

1646

AKR1C2

aldo-keto reductase family 1 member C2

protein-coding

Homo sapiens

基因描述

Type Description
Definition aldo-keto reductase family 1 member C2

研究结论

Date Results Publications
2020-10-31 13:13:00 Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation. 30886237
2020-09-05 13:53:00 Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis. 31780644
2019-04-22 10:25:00 Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid. 15383625
2018-04-21 10:05:00 Curcumin treatments considerably increased the expression of AKR1C2 in prostate cancer cell lines. 29369461
2017-12-09 11:20:00 Data show that increased levels of AKR1C1/C2 enhanced the sensitivity of esophageal squamous cell carcinoma (ESCC) cells to ethyl-3,4-dihydroxybenzoate (EDHB). 26934124

名称对应

Type IDs
Synonymous AKR1C-pseudo, BABP, DD, DD-2, DD/BABP, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8, TDD
Gene
UniProtKB-ID: AK1C2_HUMAN, B4DK69_HUMAN
UniprotKB: P52895, B4DK69
UniParc: UPI0000111D9F, UPI00017A7557, UPI0001662CC4
EMBL: AB032153, AK296686, S68330, BC007024, AL391427, BC063574, BT006653, AB021654, L32592, U05598, AK290304, AK296419, AL713867, AB031084
Ensembl: ENSG00000151632
KO: hsa:1646
Nucleutide sequences
EMBL-CDS: BAF82993.1, BAA92884.1, BAA92891.1, AAH63574.1, AAP35299.1, AAH07024.1, BAG59281.1, AAA20937.1, AAB38486.1, AAD14013.1, BAA36169.1, BAG59081.1
Ensembl_TRS: ENST00000455190, ENST00000380753, ENST00000421196
Protein sequencees
Ensembl_PRO: ENSP00000370129, ENSP00000408440, ENSP00000392694
RefSeq: NP_001345.1, NP_995317.1, NP_001307956.1, NP_001128713.1
Others
UniRef100: UniRef100_B4DK69, UniRef100_P52895
UniRef90: UniRef90_Q04828
UniRef50: UniRef50_P42330
UniGene: Hs.460260, Hs.567256, Hs.734597
CCDS: CCDS44350.1, CCDS7062.1

全选

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