| Type | Description |
|---|---|
| Definition | F11 receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 10:39:00 | Mice with total loss of JAM-A or mice with intestinal epithelial selective loss of JAM-A had increased colonic permeability and reduced polymorphonuclear neutrophils migration into the colonic lumen. These findings highlight a potentially novel role for JAM-A in regulating transepithelial migration in vivo. | 30333307 |
| 2019-09-07 10:11:00 | an increased constitutive JAM-A protein level in P2X7 receptor knockout mice may have a protective effect against bleomycin-induced lung injury. | 31075901 |
| 2019-08-31 10:06:00 | this study shows that macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice | 30745566 |
| 2019-06-29 12:05:00 | hese findings support a novel mechanism by which tyrosine phosphorylation of JAM-A Y280 regulates epithelial barrier function during inflammation. | 30625033 |
| 2019-02-02 10:36:00 | Temporary blood flow variations induce endothelial rearrangement of JAM-A, which can be visualized using JAM-A-targeted microbubbles. Thus, JAM-A may be considered as a marker of acute endothelial activation and dysfunction. | 29191926 |
| Type | IDs |
|---|---|
| Synonymous | 9130004G24, AA638916, ESTM33, JAM, JAM-1, JAM-A, Jcam, Jcam1, Ly106 |
| Gene |
UniProtKB-ID:
JAM1_MOUSE
UniprotKB:
O88792
UniParc:
UPI0000025AB4
EMBL:
AK033574,
AC087229,
U89915,
BC021876,
CT010347
Ensembl:
ENSMUSG00000038235
KO:
mmu:16456
|
| Nucleutide sequences |
EMBL-CDS:
AAC32982.1,
BAC28369.1,
CAJ18555.1,
AAH21876.1
Ensembl_TRS:
ENSMUST00000043839
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041907
RefSeq:
NP_766235.1
|
| Others |
UniRef100:
UniRef100_O88792
UniRef90:
UniRef90_O88792
UniRef50:
UniRef50_O88792
UniGene:
Mm.294882
CCDS:
CCDS15496.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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