| Type | Description |
|---|---|
| Definition | intersectin 1 (SH3 domain protein 1A) |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 10:24:00 | Data show that the ubiquitously expressed short SH3A variant of intersectin 1 interacts with an N-terminal intramolecular sequence that operates synergistically with the C-terminal motif. | 31031201 |
| 2018-12-22 11:54:00 | SH3 fusion protein pull downs using ITSN1SH3 A reveal diurnally varying binding of VGLUT1 with slightly reduced VGLUT1/dynamin ratios at the beginning of the light (ZT 0) or the dark (ZT 12) period. Phosphorylation increases binding of VGLUT1 but not of dynamin to EnphSH3. In contrast binding of dynamin to ITSN1SH3 A decreases under phosphorylating conditions with no changes in VGLUT1 binding. | 29199069 |
| 2018-05-19 11:46:00 | component of Reelin signaling that acts predominantly by facilitating the VLDLR-Dab1 axis to direct neuronal migration in the cortex and hippocampus and to augment synaptic plasticity | 28484035 |
| 2017-06-03 10:49:00 | Immunohistochemistry and histological and morphometric analyses revealed a twofold increase in proliferative endothelial cells and a 1.35-fold increase in proliferative alpha-smooth muscle actin-positive cells in the lungs of ITSN-deficient mice. | 28068512 |
| 2016-08-13 10:51:00 | PRRT2 interacts with the Src homology 3 domain-bearing protein Intersectin 1, an intracellular protein involved in synaptic vesicle cycling. | 26797119 |
| Type | IDs |
|---|---|
| Synonymous | AA517634, AA545208, AI316805, AI839402, AI848451, Ehsh1, Ese1, Itsn, Sh3p17 |
| Gene |
UniProtKB-ID:
ITSN1_MOUSE,
E9Q0N0_MOUSE,
Q6NZJ5_MOUSE,
Q8C4B5_MOUSE
UniprotKB:
Q9Z0R4,
E9Q0N0,
Q6NZJ5,
Q8C4B5
UniParc:
UPI00000E9E04,
UPI000024DBEE,
UPI000024EB18,
UPI000023B76B,
UPI0000F22184
EMBL:
BC066105,
AF356517,
AF132478,
AC126053,
AK082606,
AC131691,
AK160949,
AF132481,
AC134837,
AF169621
Ensembl:
ENSMUSG00000022957
KO:
mmu:16443
|
| Nucleutide sequences |
EMBL-CDS:
AAD19749.1,
AAD19746.1,
AAK40228.1,
AAD48848.1,
BAE36109.1,
AAH66105.1,
BAC38546.1
Ensembl_TRS:
ENSMUST00000056482,
ENSMUST00000114002,
ENSMUST00000064797,
ENSMUST00000095909
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000056011,
ENSMUSP00000109635,
ENSMUSP00000066361,
ENSMUSP00000093598
RefSeq:
NP_034717.2,
NP_001103745.1,
NP_001103746.1,
XP_006522998.1,
XP_006522996.1,
XP_006523003.1,
XP_036015688.1,
XP_006523002.1,
XP_036015687.1,
XP_006523000.1,
XP_006522997.1,
XP_006522999.1,
XP_006522994.1,
XP_036015686.1,
XP_006522995.1,
XP_006523001.1
|
| Others |
UniRef100:
UniRef100_Q6NZJ5,
UniRef100_E9Q0N0,
UniRef100_Q9Z0R4,
UniRef100_Q8C4B5
UniRef90:
UniRef90_G3U1G1,
UniRef90_Q8C4B5,
UniRef90_Q6NZJ5,
UniRef90_Q15811
UniRef50:
UniRef50_Q8C4B5,
UniRef50_Q15811,
UniRef50_Q6GMY7,
UniRef50_O42287
UniGene:
Mm.40546
CCDS:
CCDS37402.1,
CCDS49913.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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