| Type | Description |
|---|---|
| Definition | inositol 1,4,5-triphosphate receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-25 13:56:00 | Using BTBR T(+) Itpr3(tf)/J (BTBR) mice. | 31522074 |
| 2019-07-06 12:00:00 | TOM70, but not TOM20, clusters in distinct OMM foci, frequently overlapping with sites in which the endoplasmic reticulum (ER) contacts mitochondria. Functionally, TOM70 depletion specifically impairs inositol trisphosphates (IP3)-linked ER to mitochondria Ca(2+) transfer. This phenomenon is dependent on the capacity of TOM70 to interact with IP3-receptors and favor their functional recruitment close to mitochondria. | 29395920 |
| 2019-05-11 10:26:00 | InsP3R3 is dispensable for primary chemoelectrical transduction in mouse VNO. We conclude that InsP3R3 is not required for gating of Trpc2 in VSNs. | 28860523 |
| 2018-06-02 11:58:00 | Inositol 1,4,5-trisphosphate receptors (IP3Rs) are required for the hematopoietic and cardiac fate divergence of mouse embryonic stem cells. Deletion of IP3Rs (IP3R-tKO) reduced Flk1+/PDGFRalpha- hematopoietic mesoderm, c-Kit+/CD41+ hematopoietic progenitor cell population, and the colony-forming unit activity, but increased cardiac progenitor markers as well as cardiomyocytes. | 28419336 |
| 2017-09-30 13:38:00 | study demonstrated that IP3R-mediated Ca(2+) release plays an essential role in regulating B cell development, proliferation, Ab production, and B cell regulatory function in vivo | 28615414 |
| Type | IDs |
|---|---|
| Synonymous | IP3R 3, Ip3r3, Itpr-3, tf |
| Gene |
UniProtKB-ID:
ITPR3_MOUSE
UniprotKB:
P70227
UniParc:
UPI00004E1DF8
EMBL:
BC010323,
AK028491,
AB182289,
M90088,
Z71174
Ensembl:
ENSMUSG00000042644
KO:
mmu:16440
|
| Nucleutide sequences |
EMBL-CDS:
AAH10323.1,
CAA94862.1,
BAC25977.1,
BAD90683.1
Ensembl_TRS:
ENSMUST00000049308
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000038150
RefSeq:
NP_542120.2,
XP_006523775.1,
XP_036016231.1
|
| Others |
UniRef100:
UniRef100_P70227
UniRef90:
UniRef90_P70227
UniRef50:
UniRef50_P70227
UniGene:
Mm.458106
CCDS:
CCDS28560.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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