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1644 DDC

1644

DDC

dopa decarboxylase

protein-coding

Homo sapiens

基因描述

Type Description
Definition dopa decarboxylase

研究结论

Date Results Publications
2021-04-17 13:38:00 The genetic and clinical characteristics of aromatic L-amino acid decarboxylase deficiency in mainland China. 32409695
2021-03-06 13:29:00 Revised Exon Structure of l-DOPA Decarboxylase (DDC) Reveals Novel Splice Variants Associated with Colorectal Cancer Progression. 33202911
2021-02-02 13:28:00 Next-generation sequencing reveals alternative L-DOPA decarboxylase (DDC) splice variants bearing novel exons, in human hepatocellular and lung cancer cells. 33141052
2020-06-06 12:34:00 Upon hypertonic stress, in dopaminergic neural cell lines NFAT5 was activated and accumulated into the nuclei and the expression of NFAT5 increased but expression of DDC decreased. Silencing the expression of NFAT5 with a specific shRNA revealed that downregulation of DDC is independent from NFAT5. NFAT5 does not regulate the expression of the neuronal isoform of DDC in neural dopaminergic cell lines. 32165301
2020-04-04 11:06:00 A genetic variant of AADC was identified in a polymorphism that contributes to somatic symptoms in chronic pain. 31177555

名称对应

Type IDs
Synonymous AADC
Gene
UniProtKB-ID: DDC_HUMAN, A0A087WV24_HUMAN, A0A0S2Z3N4_HUMAN, Q53Y41_HUMAN
UniprotKB: P20711, A0A087WV24, A0A0S2Z3N4, Q53Y41
UniParc: UPI000013F150, UPI0000D61C41, UPI000198CE05, UPI000042486D, UPI000387DB72, UPI0000129093
EMBL: M84591, BT007009, BC000485, AC018705, M84595, AH005280, M84598, M84597, CH471128, M76180, M84596, AY526322, M84589, M84588, BC008366, S46516, KU178021, M88700, CH236955, M84590, KF511039, M84593, M84600, M84599, AJ310724, M84592, M84594
Ensembl: ENSG00000132437
KO: hsa:1644
Nucleutide sequences
EMBL-CDS: AAS01995.1, AAD40482.1, AAS00092.1, AAA58437.1, AAB59432.1, AAH08366.1, CAC84071.1, AAB23675.1, AAA20894.1, AAH00485.1, ALQ33479.1, EAW60971.1, AAP35655.1, EAW60972.1, EAW60970.1, EAL23898.1
Gene_ORFName: hCG_1811384, tcag7.584
Ensembl_TRS: ENST00000431062, ENST00000357936, ENST00000426377, ENST00000615193, ENST00000380984, ENST00000444124, ENST00000622873
Protein sequencees
Ensembl_PRO: ENSP00000350616, ENSP00000395069, ENSP00000484104, ENSP00000399184, ENSP00000403644, ENSP00000370371, ENSP00000479110
RefSeq: XP_011513463.2, NP_001229815.2, NP_001229818.2, NP_001076440.2, XP_005271802.1, NP_001229819.2, NP_001229817.2, NP_001229816.2, NP_000781.2
Others
UniRef100: UniRef100_P20711, UniRef100_A0A087WV24, UniRef100_Q53Y41
UniRef90: UniRef90_A0A3S6CS67, UniRef90_P20711
UniRef50: UniRef50_A0A3S6CS67, UniRef50_P20711
UniGene: Hs.359698
CCDS: CCDS56487.1, CCDS56485.1, CCDS5511.1

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