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16438 Itpr1

16438

Itpr1

inositol 1,4,5-trisphosphate receptor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition inositol 1,4,5-trisphosphate receptor 1

研究结论

Date Results Publications
2021-02-02 13:26:00 Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology. 32675284
2020-11-21 13:16:00 GPR40 activation initiates store-operated Ca(2+) entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic beta-cells. 31664108
2020-09-12 16:03:00 Epsin-mediated degradation of IP3R1 fuels atherosclerosis. 32770009
2020-07-11 11:43:00 The level and phosphorylation of IP3R1 is reduced to a variable degree in the different HD models relative to control, indicating that earlier findings in more aggressive exon 1-truncated Huntington Disease models may not be replicated in models with higher construct validity. 31256144
2020-07-11 10:20:00 Data suggest that dysregulation of ITPR1 in the cerebellum could be one of contributing factors to progressive ataxia. 32123907

名称对应

Type IDs
Synonymous D6Pas2, Gm10429, IP3R 1, IP3R1, InsP3R, Ip3r, Itpr-1, P400, Pcp-1, Pcp1, insP3R1, opt, wblo
Gene
UniProtKB-ID: ITPR1_MOUSE, Q8C8N0_MOUSE, Q8C7X9_MOUSE, Q8BQN0_MOUSE, Q3UVA1_MOUSE
UniprotKB: P11881, Q8C8N0, Q8C7X9, Q8BQN0, Q3UVA1
UniParc: UPI00000E9874, UPI00000EAF1A, UPI0000F4F5AC, UPI00015DEF74, UPI0001E88EBD, UPI0001E88EBC, UPI0001E88EBB, UPI0000F4F57B, UPI0001E88EBE, UPI0000F4F59C, UPI00005ABD83, UPI00000E9966
EMBL: X15373, AK044776, AK047719, AC156506, AC153986, M75987, AC120411, AK137477, M21530, M75986, AK049015, BC003271
Ensembl: ENSMUSG00000030102
KO: mmu:16438
Nucleutide sequences
EMBL-CDS: AAH03271.1, AAA39316.1, AAA88319.1, CAA33433.1, AAA39317.1, BAC32085.1, BAC33514.1, BAC33138.1, BAE23370.1
Ensembl_TRS: ENSMUST00000203615, ENSMUST00000032192
Protein sequencees
Ensembl_PRO: ENSMUSP00000144880, ENSMUSP00000032192
RefSeq: XP_036021776.1, XP_006505696.1, XP_030111059.1, XP_017176898.1, NP_034715.3, XP_006505694.1, XP_006505700.1, XP_006505695.1, XP_017176897.1, XP_006505688.1, XP_006505691.1, XP_017176896.1, XP_006505690.1, XP_017176899.1, XP_006505699.1, XP_006505687.1, XP_006505693.1, XP_006505692.1, XP_006505689.1, XP_006505686.1
Others
UniRef100: UniRef100_P11881, UniRef100_A0A6P7RCC6, UniRef100_Q8C7X9, UniRef100_A0A3B3ITM1, UniRef100_Q3UVA1
UniRef90: UniRef90_Q3UVA1, UniRef90_P11881, UniRef90_A0A2I3TCW5, UniRef90_A0A6P7RCC6
UniRef50: UniRef50_A0A2I3TCW5, UniRef50_P29994-8, UniRef50_P11881
UniGene: Mm.227912
CCDS: CCDS51869.1

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