| Type | Description |
|---|---|
| Definition | IL2 inducible T cell kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:31:00 | Interleukin-2-Inducible T-Cell Kinase Deficiency Impairs Early Pulmonary Protection Against Mycobacterium tuberculosis Infection. | 32038633 |
| 2020-10-10 12:58:00 | CD8(+) T Cells Require ITK-Mediated TCR Signaling for Migration to the Intestine. | 32034085 |
| 2020-07-04 10:58:00 | Ibrutinib suppressed phosphorylation of BTK in neutrophils at lower doses and ITK in CD4+T cells at higher doses in CE-treated mice. | 31505252 |
| 2019-05-04 13:00:00 | Inhibition of ITK and RLK attenuated psoriasis-associated signaling pathways, indicating that PRN694 is an effective psoriasis therapeutic. | 29129599 |
| 2019-01-19 11:03:00 | ITK signalling through the Ras/IRF4 pathway is required for functional development of type 1 regulatory T cells. | 28635957 |
| Type | IDs |
|---|---|
| Synonymous | Emt, Tcsk, Tsk |
| Gene |
UniProtKB-ID:
ITK_MOUSE,
A1A560_MOUSE,
Q5STT7_MOUSE,
Q3U5G1_MOUSE,
Q5STT8_MOUSE
UniprotKB:
Q03526,
A1A560,
Q5STT7,
Q3U5G1,
Q5STT8
UniParc:
UPI000016D084,
UPI0000EA2A72,
UPI0000196386,
UPI0000029AA4,
UPI00005ACCE5
EMBL:
L05631,
BC128374,
L00619,
D14042,
BC128375,
AK153613,
AL662806,
L10628
Ensembl:
ENSMUSG00000020395
KO:
mmu:16428
|
| Nucleutide sequences |
EMBL-CDS:
AAA39337.1,
AAA40518.1,
BAA03129.1,
AAI28376.1,
BAE32118.1,
AAI28375.1
Ensembl_TRS:
ENSMUST00000109237,
ENSMUST00000101306,
ENSMUST00000020664
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104860,
ENSMUSP00000098864,
ENSMUSP00000020664
RefSeq:
NP_001268896.1,
NP_001268895.1,
NP_001268894.1,
NP_034713.2,
NP_001268897.1
|
| Others |
UniRef100:
UniRef100_Q5STT8,
UniRef100_Q5STT7,
UniRef100_Q3U5G1,
UniRef100_Q03526,
UniRef100_A1A560
UniRef90:
UniRef90_Q5STT7,
UniRef90_Q08881
UniRef50:
UniRef50_Q5STT7,
UniRef50_Q08881
UniGene:
Mm.339927
CCDS:
CCDS70169.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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