| Type | Description |
|---|---|
| Definition | damage specific DNA binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer. | 32739133 |
| 2021-03-06 13:32:00 | CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy. | 32466489 |
| 2021-02-27 13:53:00 | Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex. | 32235678 |
| 2021-02-27 13:45:00 | Discovery of a molecular glue promoting CDK12-DDB1 interaction to trigger cyclin K degradation. | 32804079 |
| 2020-07-18 12:23:00 | Thalidomide-dependent degradation of the embryonic transcription factor SALL4 by the CRL4(CRBN) E3 ubiquitin ligase is a plausible major driver of thalidomide teratogenicity. The structure of the second zinc finger of SALL4 in complex with pomalidomide, cereblon and DDB1 reveals the molecular details of recruitment. | 32251415 |
| Type | IDs |
|---|---|
| Synonymous | DDBA, UV-DDB1, XAP1, XPCE, XPE, XPE-BF |
| Gene |
UniProtKB-ID:
DDB1_HUMAN
UniprotKB:
Q16531
UniParc:
UPI00017A707E,
UPI0000000CB7
EMBL:
AK294341,
CH471076,
L40326,
AK312436,
AP003108,
U18299,
AP003037,
BC011686,
U32986,
AJ002955,
BC051764,
BC050530,
AY960579
Ensembl:
ENSG00000167986
KO:
hsa:1642
|
| Nucleutide sequences |
EMBL-CDS:
CAA05770.1,
AAH11686.1,
AAA88883.1,
AAC50349.1,
BAG57611.1,
AAH50530.1,
AAX44048.1,
EAW73935.1,
AAA62838.1,
AAH51764.1,
BAG35345.1
Ensembl_TRS:
ENST00000301764
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301764
RefSeq:
NP_001914.3
|
| Others |
UniRef100:
UniRef100_Q16531
UniRef90:
UniRef90_Q16531
UniRef50:
UniRef50_Q16531
UniGene:
Hs.290758
CCDS:
CCDS31576.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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