| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 6 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-14 11:12:00 | eIF6 heterozygous mice show an increased mortality during viral infection and a reduction of peripheral blood CD4(+) effector memory T cells | 28743432 |
| 2018-05-05 10:56:00 | Taken together, these results indicate that eIF6 may be involved in external mechanical force-mediated murine dermal fibroblast function at least partly through the TGF-beta1/TGFBR1/TGFBR2 pathway. | 27824055 |
| 2017-04-08 10:15:00 | eIF6 relieved fibrosis/cicatrization by inhibiting the generation of VEGF to prevent the overgrowth of blood vessels and production of granulation tissues, and by regulating the MMP-2/TIMP-2 balance to promote ECM degradation and decrease its deposition. | 27220600 |
| 2016-09-24 11:55:00 | data reveal a novel transcriptional regulatory mechanism of eIF6 that acts on facilitating Sp1 recruitment to TGF-beta1 promoter via H2A.Z depletion and thus results in increased TGF-beta1 transcription, which contributes to myofibroblast differentiation. | 26395397 |
| 2016-09-17 10:13:00 | Reduced eIF6 expression negatively impacts on megakaryopoiesis. in eIF6(+/-) cells, the steady-state abundance of mitochondrial respiratory chain complex I-encoding mRNAs is decreased, resulting in decreased reactive oxygen species production. | 26391622 |
| Type | IDs |
|---|---|
| Synonymous | 1110004P11, AA408895, CAB, Itgb4bp, eIF-6, imc-415, p27(BBP), p27BBP |
| Gene |
UniProtKB-ID:
IF6_MOUSE,
Q545K4_MOUSE
UniprotKB:
O55135,
Q545K4
UniParc:
UPI000000195E
EMBL:
AK168257,
AK003447,
AK012218,
AK165946,
AK150400,
AK152093,
AF047046,
BC015274,
BC024442,
AK151644,
AK150720,
AK159157,
AK167422,
AK134364,
AK007594,
Y11460,
AK151089,
AK088707,
AK151102
Ensembl:
ENSMUSG00000027613
KO:
mmu:16418
|
| Nucleutide sequences |
EMBL-CDS:
AAH15274.1,
CAA72246.1,
AAD28078.1,
AAH24442.1,
BAE30574.1,
BAE39510.1,
BAB28105.1,
BAE38478.1,
BAE30102.1,
BAE34862.1,
BAE22116.1,
BAE30941.1,
BAB22796.1,
BAB25125.1,
BAE29526.1,
BAE30112.1,
BAE40205.1,
BAE29798.1,
BAC40517.1
Ensembl_TRS:
ENSMUST00000029142
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029142
RefSeq:
NP_034709.1
|
| Others |
UniRef100:
UniRef100_O55135
UniRef90:
UniRef90_P56537
UniRef50:
UniRef50_P56537
UniGene:
Mm.271674
CCDS:
CCDS16956.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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