Type | Description |
---|---|
Definition | doublecortin |
Date | Results | Publications |
---|---|---|
2020-06-27 10:35:00 | Study shows the DCX E2K mutant protein retains the ability to interact with and bundle microtubules (MT)s, but these MTs show a reduced sensitivity to nocodazole-induced depolymerization as well as slower alpha-tubulin exchange rates. Also shows increased association of DCX E2K mutant with the actin filament (F-ACT) network. | 30979500 |
2020-05-16 11:29:00 | this is the first report revealing that cir-CCDC66 modulates DCX expression through sponging miR-488-3p and thus participates in the onset of Hirschsprung's disease. | 30443988 |
2019-11-16 11:36:00 | Phosphorylation of dublecortin X (DCX) serine 28 (S28) plays a critical role in DCX association with the cytoskeleton in human neuroblastoma cells. | 30625347 |
2019-04-20 11:32:00 | Doublecortin can associate with AP-2 without being bound to microtubules. A DCX-G35D mutation causes a dominant-negative dendrite growth phenotype that is not due to a defect in neurofascin endocytosis. | 30291144 |
2019-03-09 10:41:00 | exchange rates for the C-terminal truncated DCX protein were resistant to the impact of taxol-induced stabilization | 28701724 |
Type | IDs |
---|---|
Synonymous | DBCN, DC, LISX, SCLH, XLIS |
Gene |
UniProtKB-ID:
DCX_HUMAN,
A8K340_HUMAN
UniprotKB:
O43602,
A8K340
UniParc:
UPI000002A7C9,
UPI00000012B0,
UPI00015DA706
EMBL:
AJ005594,
AJ005596,
AJ003112,
AJ005592,
AF040254,
AL031117,
AK290455,
AL450490,
AF034634,
AJ005593,
BC027925,
CH471120,
AF040255,
AJ005595,
AJ005597
Ensembl:
ENSG00000077279
KO:
hsa:1641
|
Nucleutide sequences |
EMBL-CDS:
CAA06617.1,
EAX02643.1,
AAH27925.1,
AAC31797.1,
EAX02647.1,
AAC31696.1,
EAX02649.1,
AAC52037.1,
EAX02645.1,
CAA05867.1,
EAX02644.1,
EAX02646.1,
EAX02642.1,
BAF83144.1
Ensembl_TRS:
ENST00000488120,
ENST00000358070,
ENST00000635795,
ENST00000496551,
ENST00000371993,
ENST00000637453,
ENST00000356220,
ENST00000636035
|
Protein sequencees |
Ensembl_PRO:
ENSP00000419861,
ENSP00000350776,
ENSP00000361061,
ENSP00000490448,
ENSP00000489635,
ENSP00000490357,
ENSP00000348553,
ENSP00000490614
RefSeq:
NP_001182482.1,
NP_835365.1,
NP_001356300.1,
NP_001356299.1,
NP_835366.1,
NP_000546.2,
XP_011529181.1,
NP_001356303.1,
NP_001356302.1,
NP_835364.1,
NP_001356301.1
|
Others |
UniRef100:
UniRef100_A8K340,
UniRef100_O43602
UniRef90:
UniRef90_O43602,
UniRef90_O88809
UniRef50:
UniRef50_O43602,
UniRef50_O88809
UniGene:
Hs.34780
CCDS:
CCDS14557.1,
CCDS14558.1
|
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