| Type | Description |
|---|---|
| Definition | integrin alpha 7 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-20 11:23:00 | Ptrh2 levels were up-regulated in dystrophin deficient mdx muscle, which correlates with the elevated levels of the a7b1 integrin observed in mdx muscle and Duchenne muscular dystrophy patients. Similar to the a7 integrin, Ptrh2 expression was decreased in laminin-a2 null gastrocnemius muscle | 28175314 |
| 2016-08-06 11:23:00 | Deletion of integrin alpha7 subunit does not aggravate the phenotype of laminin alpha2 chain-deficient mice. laminin-211 and integrin alpha7beta1 have intersecting roles in skeletal muscle. | 26355035 |
| 2016-01-16 11:10:00 | Sarcospan-mediated amelioration of muscular dystrophy in mouse model is dependent on the presence of both utrophin and alpha7beta1 integrin. | 25504048 |
| 2013-06-22 10:05:00 | loss of alpha7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice | 22798625 |
| 2011-12-24 10:53:00 | alpha7 integrin prevents muscle disease progression through augmentation and/or stabilization of the existing extracellular matrix in laminin-alpha2-deficient mice and might be a novel drug target for the treatment of MDC1A. | 21652631 |
| Type | IDs |
|---|---|
| Synonymous | [a]7, alpha7 |
| Gene |
UniProtKB-ID:
Q3TZS3_MOUSE,
G3X9Q1_MOUSE
UniprotKB:
Q3TZS3,
G3X9Q1
UniParc:
UPI0000565381,
UPI000024DCD2
EMBL:
AC122380,
AK157612
Ensembl:
ENSMUSG00000025348
KO:
mmu:16404
|
| Nucleutide sequences |
EMBL-CDS:
BAE34134.1
Ensembl_TRS:
ENSMUST00000218290,
ENSMUST00000099112
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000151960,
ENSMUSP00000096712
RefSeq:
NP_032424.2,
XP_030100773.1,
XP_030100775.1,
XP_030100774.1,
XP_036011542.1,
XP_030100776.1,
XP_006513332.1,
XP_017169302.1,
NP_001317089.1,
XP_006513333.1
|
| Others |
UniRef100:
UniRef100_Q3TZS3,
UniRef100_G3X9Q1
UniRef90:
UniRef90_Q3TZS3
UniRef50:
UniRef50_Q13683
UniGene:
Mm.179747
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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