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163859 SDE2

163859

SDE2

SDE2 telomere maintenance homolog

protein-coding

Homo sapiens

基因描述

Type Description
Definition SDE2 telomere maintenance homolog

研究结论

Date Results Publications
2020-11-21 13:23:00 SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks. 33127907
2019-11-30 11:06:00 Conditional degradation of SDE2 by the Arg/N-End rule pathway regulates stress response at replication forks. 30698750
2017-05-13 18:43:00 collectively, this study uncovers a new role for CRL4CDT2 in protecting genomic integrity against replication stress via regulated proteolysis of PCNA-associated SDE2 and provides insights into how an integrated UBL domain within linear polypeptide sequence controls protein stability and function. 27906959

名称对应

Type IDs
Synonymous C1orf55, dJ671D7.1
Gene
UniProtKB-ID: SDE2_HUMAN
UniprotKB: Q6IQ49
UniParc: UPI0000470AF8, UPI00014F7AC1, UPI0000204007
EMBL: AK092701, AL133288, AK291008, AK127780, CH471098, BC071563
Ensembl: ENSG00000143751
KO: hsa:163859
Nucleutide sequences
EMBL-CDS: BAC87130.1, BAF83697.1, AAH71563.1, BAC03952.1, EAW69769.1
Ensembl_TRS: ENST00000272091
Protein sequencees
Ensembl_PRO: ENSP00000272091
RefSeq: NP_689821.3
Others
UniRef100: UniRef100_Q6IQ49
UniRef90: UniRef90_Q6IQ49
UniRef50: UniRef50_Q6IQ49
UniGene: Hs.520192
CCDS: CCDS41473.1

全选

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研究热度

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