| Type | Description |
|---|---|
| Definition | dopachrome tautomerase |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:05:00 | TGF-beta and GLI2-specific TRP2 repression in melanoma cells involves direct mechanisms that occur in addition to MITF downregulation by TGF-beta and GLI2. Two functional GLI2 binding sites identified within the TRP2 promoter that are critical for TGF-beta and GLI2 responsiveness, one of them overlapping a CREB binding site. GLI2 and CREB competing for the same cis-element is associated with opposite transcriptional ou... | 31208857 |
| 2018-06-30 10:53:00 | High DCT expression is associated with progressive multiple sclerosis. | 28923927 |
| 2017-08-19 10:28:00 | High DCT expression is associated with HPV16 Infection. | 28095444 |
| 2016-12-17 11:48:00 | Data indicate that the caveolin-1 (CAV1) control on dopachrome tautomerase (DCT) gene expression, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent. | 27053106 |
| 2015-08-01 11:24:00 | The effect of DCT on UVR DNA damage responses and survival pathways in melanocytes was examined by knockdown experiments using melanoma cells, neonatal melanoblasts in monoculture and in co-culture with keratinocytes. | 25346513 |
| Type | IDs |
|---|---|
| Synonymous | TRP-2, TYRP2 |
| Gene |
UniProtKB-ID:
TYRP2_HUMAN
UniprotKB:
P40126
UniParc:
UPI0000000A09,
UPI0000E13F02
EMBL:
D17547,
AL139318,
L18967,
BC028311,
S69231,
DQ902581,
D28767,
L38953
Ensembl:
ENSG00000080166
KO:
hsa:1638
|
| Nucleutide sequences |
EMBL-CDS:
AAC41925.1,
AAA20870.1,
BAA04484.1,
AAC60627.1,
AAH28311.1,
ABI73976.1,
BAA05956.1
Ensembl_TRS:
ENST00000446125,
ENST00000377028
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366227,
ENSP00000392762
RefSeq:
NP_001123361.1,
NP_001309112.1,
NP_001309111.1,
NP_001309115.1,
XP_011519351.1,
XP_024305096.1,
NP_001913.2,
NP_001309113.1,
NP_001309114.1,
XP_016875890.1
|
| Others |
UniRef100:
UniRef100_P40126
UniRef90:
UniRef90_P40126
UniRef50:
UniRef50_P29812
UniGene:
Hs.301865
CCDS:
CCDS45060.1,
CCDS9470.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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