| Type | Description |
|---|---|
| Definition | SAS-6 centriolar assembly protein |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:49:00 | The ubiquitin ligase FBXW7 targets the centriolar assembly protein HsSAS-6 for degradation and thereby regulates centriole duplication. | 32086376 |
| 2020-09-19 16:25:00 | CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation. | 31722219 |
| 2020-02-08 12:52:00 | Expression regulation of PLK-4 and SAS-6 has a central role in centriole biogenesis. (Review) | 30787112 |
| 2019-03-23 11:37:00 | the role of SASS6 in the pathogenesis of microcephaly | 30639237 |
| 2017-07-15 10:26:00 | Studies indicate that depletion of any one of the protein kinase polo-like kinase 4 (PLK4) and the two proteins STIL and SAS-6 blocks centriole duplication, and, conversely, overexpression causes centriole amplification. | 27911707 |
| Type | IDs |
|---|---|
| Synonymous | MCPH14, SAS-6, SAS6 |
| Gene |
UniProtKB-ID:
SAS6_HUMAN,
Q495U0_HUMAN,
B4DYM7_HUMAN
UniprotKB:
Q6UVJ0,
Q495U0,
B4DYM7
UniParc:
UPI00017A80DA,
UPI00001BDF30,
UPI000058E056
EMBL:
AL834265,
AL445928,
AC093019,
CH471097,
AY359522,
BC101026,
AK302513
Ensembl:
ENSG00000156876
KO:
hsa:163786
|
| Nucleutide sequences |
EMBL-CDS:
AAQ57128.1,
EAW72975.1,
CAD38940.1,
EAW72974.1,
AAI01027.1,
BAG63789.1
Ensembl_TRS:
ENST00000287482
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000287482
RefSeq:
XP_016855975.1,
NP_919268.1,
NP_001291758.1
|
| Others |
UniRef100:
UniRef100_Q6UVJ0,
UniRef100_Q495U0
UniRef90:
UniRef90_Q495U0,
UniRef90_Q6UVJ0
UniRef50:
UniRef50_Q6UVJ0,
UniRef50_G7MI54
UniGene:
Hs.591447
CCDS:
CCDS764.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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