| Type | Description |
|---|---|
| Definition | insulin receptor substrate 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:26:00 | Paraventricular, subparaventricular and periventricular hypothalamic IRS4-expressing neurons are required for normal energy balance. | 32218485 |
| 2019-03-16 11:31:00 | our results give the first functional evidence for IRS4 as a critical regulator of BMP/Smad and Akt signalling in the context of muscle differentiation. | 28821740 |
| 2014-09-20 12:15:00 | conclude that Y103 is required for the internalization of hCTR1 in response to Cu, that this occurs by a mechanism other than phosphorylation and that mutation of Y103 modulates the interaction with IRS-4 | 24967972 |
| 2014-07-05 10:53:00 | Down-regulation of the insulin receptor substrate 4 (Irs4) gene, may be an important event in the transition from age-related changes to Alzheimer's disease specific-changes. | 24274089 |
| 2010-01-21 00:00:00 | These data indicate that both insulin receptor substrate (IRS)-1 and -3, but not IRS-2 or IRS-4, play key roles in the differentiation of brown adipocytes. | 14966273 |
| Type | IDs |
|---|---|
| Synonymous | IRS-4 |
| Gene |
UniProtKB-ID:
IRS4_MOUSE
UniprotKB:
Q9Z0Y7
UniParc:
UPI000024F7B0
EMBL:
AF087797,
AK045172,
BX571779
Ensembl:
ENSMUSG00000054667
KO:
mmu:16370
|
| Nucleutide sequences |
EMBL-CDS:
AAD17797.1,
BAC32246.1
Ensembl_TRS:
ENSMUST00000067841
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067085
RefSeq:
NP_034702.2
|
| Others |
UniRef100:
UniRef100_Q9Z0Y7
UniRef90:
UniRef90_Q9Z0Y7
UniRef50:
UniRef50_O14654
UniGene:
Mm.261591
CCDS:
CCDS30445.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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