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16363 Irf2

16363

Irf2

interferon regulatory factor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition interferon regulatory factor 2

研究结论

Date Results Publications
2021-03-06 13:28:00 IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon. 32901054
2020-07-04 10:32:00 Data show that interferon regulatory factor 2 (IRF2), a member of the interferon regulatory factor (IRF) family of transcription factors, was essential for the transcriptional activation of gasdermin-D (GSDMD). 31113851
2020-04-11 10:56:00 The results point to a unique, cell-type selective role for IRF-2 in Innate lymphoid cells (ILC) development, acting at a discrete step critical for the generation of functionally competent Innate lymphoid cells precursors (ILCPs). 30783658
2020-02-08 10:07:00 The KRAS( *)-IRF2-CXCL3-CXCR2 axis drives colorectal cancer cell immune suppression and resistance to anti-PD-1 immunotherapy. 30905761
2019-04-13 10:53:00 our data suggest that IRF2 is an important regulator of the proinflammatory response in macrophages by controlling HIF-1alpha-dependent glycolytic gene expression and glycolysis. 29563175

名称对应

Type IDs
Synonymous 9830146E22Rik, AI646973, Irf-2
Gene
UniProtKB-ID: IRF2_MOUSE, Q3U2Z2_MOUSE
UniprotKB: P23906, Q3U2Z2
UniParc: UPI000002A120
EMBL: AK155025, J03168
Ensembl: ENSMUSG00000031627
KO: mmu:16363
Nucleutide sequences
EMBL-CDS: AAA39333.1, BAE32998.1
Ensembl_TRS: ENSMUST00000034041
Protein sequencees
Ensembl_PRO: ENSMUSP00000034041
RefSeq: XP_017168069.1, XP_030099166.1, XP_011240477.1, XP_006509352.1, XP_030099165.1, NP_032417.3, XP_006509351.1
Others
UniRef100: UniRef100_P23906
UniRef90: UniRef90_P23906
UniRef50: UniRef50_P14316
UniGene: Mm.1149
CCDS: CCDS22295.1

全选

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研究热度

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