| Type | Description |
|---|---|
| Definition | adaptor related protein complex 2 subunit beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-24 12:18:00 | Reduced expression of AP-2beta was significantly associated with more advanced hepatocellular carcinoma stages and larger tumor sizes. The overexpression of AP-2beta reduced HCC proliferation, migration, invasion, tumor formation and metastasis in vitro and in vivo. Moreover, AP-2beta modulates the levels of epithelial-mesenchymal transition markers through Slug and Snail in hepatocellular carcinoma cell lines and tiss... | 30026878 |
| 2019-01-26 11:14:00 | AP2B1 might be associated with the development of nonsyndromic cleft lip with or without cleft palate. | 30411541 |
| 2014-08-09 11:14:00 | this study determined a structure of AP2 that includes the clathrin-binding beta2 hinge. | 25061211 |
| 2012-04-26 16:08:00 | A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration. | 22360420 |
| 2010-05-07 14:34:00 | Results suggest that autosomal recessive hypercholesterolemia (ARH) and beta-arrestin depend on a privileged AP2beta2 appendage site for proper cargo recruitment to clathrin bud sites. | 18843039 |
| Type | IDs |
|---|---|
| Synonymous | ADTB2, AP105B, AP2-BETA, CLAPB1 |
| Gene |
UniProtKB-ID:
AP2B1_HUMAN,
A0A140VJE8_HUMAN,
Q96EL6_HUMAN
UniprotKB:
P63010,
A0A140VJE8,
Q96EL6
UniParc:
UPI000006CDEB,
UPI00001BB2A2,
UPI000006DD97,
UPI0000125012
EMBL:
BC012150,
CH471147,
M34175,
HM005335,
BC006201,
AC006237,
AC004134,
AY341427,
AC015911
Ensembl:
ENSG00000006125
KO:
hsa:163
|
| Nucleutide sequences |
EMBL-CDS:
AAQ20044.1,
EAW80139.1,
EAW80133.1,
AAA35583.1,
AAH06201.1,
EAW80141.1,
AEE60935.1,
AAH12150.1
Gene_ORFName:
hCG_1992160
Ensembl_TRS:
ENST00000610402,
ENST00000618940,
ENST00000621914
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000483185,
ENSP00000482835,
ENSP00000482315
RefSeq:
XP_011522754.1,
XP_011522750.1,
XP_011522752.1,
XP_016879774.1,
XP_011522753.1,
XP_005257998.1,
NP_001273.1,
XP_011522756.1,
XP_005257994.1,
NP_001025177.1,
XP_005257995.1,
XP_016879775.1,
XP_016879773.1,
XP_011522755.1,
XP_016879776.1,
XP_011522751.1,
XP_011522757.1
|
| Others |
UniRef100:
UniRef100_A0A140VJE8,
UniRef100_P63010,
UniRef100_Q08DS7
UniRef90:
UniRef90_Q08DS7,
UniRef90_A0A140VJE8,
UniRef90_P63010
UniRef50:
UniRef50_P63010,
UniRef50_O81742
UniGene:
Hs.514819
CCDS:
CCDS32622.1,
CCDS32621.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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