例如:"NBL1", "4681", "drought"
收藏
162515 SLC16A11

162515

SLC16A11

solute carrier family 16 member 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition solute carrier family 16 member 11

研究结论

Date Results Publications
2020-08-12 15:45:00 The previously reported effects of SLC16A11 variants shown to be associated with diabetes in Mexicans was replicated in a large Mexican-American sample, but these effects were not significant in five non-Mexican Hispanic/Latino groups sampled from U.S. populations. 30696834
2019-03-02 10:48:00 Individuals carrying the SLC16A11 risk haplotype exhibited decreased insulin action. Higher serum ALT and GGT levels were found in carriers with type 2 diabetes, and larger adipocytes in subcutaneous fat in the size distribution in carrier women with normal weight. 30475225
2018-07-14 10:08:00 rs13342232 might be involved in the risk of pediatric-onset type 2 diabetes in Mexican families 28101933
2017-08-05 10:11:00 Study demonstrates that disruption of SLC16A11 in primary human hepatocytes leads to Type 2 diabetes (T2D)-relevant changes in fatty acid and lipid metabolism; these results implicate reduced SLC16A11 function in liver as a causal factor for T2D. 28666119
2016-06-04 10:50:00 Our study identified an association between the SLC16A11 variant rs75493593 and type 2 diabetes in American Indians, where the effect on diabetes was much more pronounced in nonobese individuals. rs75493593 was also associated with RNASEK gene expression. 26487785

名称对应

Type IDs
Synonymous MCT 11, MCT11
Gene
UniProtKB-ID: MOT11_HUMAN
UniprotKB: Q8NCK7
UniParc: UPI000006F985
EMBL: BC093860, AK074674, BC093886
Ensembl: ENSG00000174326
KO: hsa:162515
Nucleutide sequences
EMBL-CDS: AAH93860.1, BAC11128.1, AAH93886.1
Ensembl_TRS: ENST00000308009
Protein sequencees
Ensembl_PRO: ENSP00000310490
RefSeq: NP_001357482.1, NP_001357478.1, NP_699188.2, XP_016879771.1
Others
UniRef100: UniRef100_Q8NCK7
UniRef90: UniRef90_Q8NCK7
UniRef50: UniRef50_Q8NCK7
UniGene: Hs.336564

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员