Type | Description |
---|---|
Definition | solute carrier family 16 member 11 |
Date | Results | Publications |
---|---|---|
2020-08-12 15:45:00 | The previously reported effects of SLC16A11 variants shown to be associated with diabetes in Mexicans was replicated in a large Mexican-American sample, but these effects were not significant in five non-Mexican Hispanic/Latino groups sampled from U.S. populations. | 30696834 |
2019-03-02 10:48:00 | Individuals carrying the SLC16A11 risk haplotype exhibited decreased insulin action. Higher serum ALT and GGT levels were found in carriers with type 2 diabetes, and larger adipocytes in subcutaneous fat in the size distribution in carrier women with normal weight. | 30475225 |
2018-07-14 10:08:00 | rs13342232 might be involved in the risk of pediatric-onset type 2 diabetes in Mexican families | 28101933 |
2017-08-05 10:11:00 | Study demonstrates that disruption of SLC16A11 in primary human hepatocytes leads to Type 2 diabetes (T2D)-relevant changes in fatty acid and lipid metabolism; these results implicate reduced SLC16A11 function in liver as a causal factor for T2D. | 28666119 |
2016-06-04 10:50:00 | Our study identified an association between the SLC16A11 variant rs75493593 and type 2 diabetes in American Indians, where the effect on diabetes was much more pronounced in nonobese individuals. rs75493593 was also associated with RNASEK gene expression. | 26487785 |
Type | IDs |
---|---|
Synonymous | MCT 11, MCT11 |
Gene |
UniProtKB-ID:
MOT11_HUMAN
UniprotKB:
Q8NCK7
UniParc:
UPI000006F985
EMBL:
BC093860,
AK074674,
BC093886
Ensembl:
ENSG00000174326
KO:
hsa:162515
|
Nucleutide sequences |
EMBL-CDS:
AAH93860.1,
BAC11128.1,
AAH93886.1
Ensembl_TRS:
ENST00000308009
|
Protein sequencees |
Ensembl_PRO:
ENSP00000310490
RefSeq:
NP_001357482.1,
NP_001357478.1,
NP_699188.2,
XP_016879771.1
|
Others |
UniRef100:
UniRef100_Q8NCK7
UniRef90:
UniRef90_Q8NCK7
UniRef50:
UniRef50_Q8NCK7
UniGene:
Hs.336564
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员