| Type | Description |
|---|---|
| Definition | integrin linked kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:23:00 | Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin. | 31330146 |
| 2020-08-22 15:26:00 | L1CAM-ILK-YAP Mechanotransduction Drives Proliferative Activity of Epithelial Cells in Middle Ear Cholesteatoma. | 32360569 |
| 2020-06-20 11:39:00 | ILK was highly expressed in unilateral ureteral obstruction (UUO) model in CD1 mice. Renal fibrosis was aggravated after injection of ILK overexpression plasmid in UUO mice. Western blot results showed that expressions of p-smad3 and smad3 were upregulated during renal fibrosis. ILK participates in the development of renal fibrosis by altering phenotypes of renal tubular epithelial cells via a TGF-beta1/smad pathway. | 30657569 |
| 2020-06-06 13:05:00 | critical involvement of ILK in necroptosis through modulation of the RIPK3 and MLKL pathway and highlights the contribution of Collecting Duct Principal Cell injury to the development of inflammation and interstitial fibrosis of the kidney. | 31653783 |
| 2020-03-07 11:08:00 | ILK, a mediator of cell-matrix interactions, is indispensable for retinal angiogenesis. Inactivation of the murine Ilk gene in postnatal endothelial cells results in sprouting defects, reduced endothelial proliferation and disruption of the blood-retina barrier, resembling phenotypes seen in established mouse models of Familial exudative vitreoretinopathy. | 31748531 |
| Type | IDs |
|---|---|
| Synonymous | AA511515, ESTM24 |
| Gene |
UniProtKB-ID:
ILK_MOUSE
UniprotKB:
O55222
UniParc:
UPI0000023621
EMBL:
U94479,
BC003737
Ensembl:
ENSMUSG00000030890
KO:
mmu:16202
|
| Nucleutide sequences |
EMBL-CDS:
AAB94646.1,
AAH03737.1
Ensembl_TRS:
ENSMUST00000163389,
ENSMUST00000033182
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033182,
ENSMUSP00000130341
RefSeq:
NP_001155196.1,
NP_034692.2
|
| Others |
UniRef100:
UniRef100_O55222
UniRef90:
UniRef90_O55222
UniRef50:
UniRef50_O55222
UniGene:
Mm.274846
CCDS:
CCDS21659.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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