| Type | Description |
|---|---|
| Definition | BMP/retinoic acid inducible neural specific 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-24 11:15:00 | Results found that the expression of DBCCR1 is significantly lower in the lung cancer tissues compared with adjacent non-tumor tissues of patients, and correlates with more advanced stages of cancer, and shorter survival of patients. Interestingly, DBCCR1 attenuates the expression of DNMT1, suggesting a reciprocal regulation between genetic silencing of cancer suppressor genes and activating DNA methylation. | 28427182 |
| 2013-07-20 11:23:00 | we found that the SIRT1 modulators and DBC1 have an impact on hsp70 transcription, HSF1 acetylation status, and HSF1 recruitment to the hsp70 promoter | 23349863 |
| 2013-06-01 10:39:00 | DBC1 modulates the stability and function of the nuclear receptor Rev-erb-alpha. | 23398316 |
| 2012-06-16 11:27:00 | the stress-induced DBC1-SIRT1 interaction is important for cell fate determination following genotoxic stress. | 22465953 |
| 2011-02-26 11:10:00 | Rxpression of DBC1 and SIRT1 is a significant prognostic indicator for breast carcinoma patients. | 21056897 |
| Type | IDs |
|---|---|
| Synonymous | DBC1, DBCCR1, FAM5A |
| Gene |
UniProtKB-ID:
BRNP1_HUMAN
UniprotKB:
O60477
UniParc:
UPI000013D6A7,
UPI000037830E,
UPI000007017C
EMBL:
BC021560,
BC071702,
AF027734,
AL138894,
BC065196,
AL353773
Ensembl:
ENSG00000078725
KO:
hsa:1620
|
| Nucleutide sequences |
EMBL-CDS:
AAC39691.1,
AAH71702.1,
AAH65196.1,
AAH21560.1
Gene_ORFName:
IB3089A
Ensembl_TRS:
ENST00000373964,
ENST00000265922
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265922,
ENSP00000363075
RefSeq:
NP_055433.2
|
| Others |
UniRef100:
UniRef100_O60477
UniRef90:
UniRef90_O60477
UniRef50:
UniRef50_Q920P3
UniGene:
Hs.532316
CCDS:
CCDS6822.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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