| Type | Description |
|---|---|
| Definition | fibrous sheath interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:03:00 | Loss-of-function variants in FSIP1 identified by targeted sequencing are associated with one particular subtype of mucosal melanoma. | 32717308 |
| 2020-06-06 12:24:00 | FSIP1 bound to the multidrug resistance protein 1 (MRP1) and stabilized it, and knocking out FSIP1 decreased MRP1 expression and increased cellular docetaxel accumulation. In sum, FSIP1 promotes breast carcinogenesis and mediates docetaxel resistance. | 30814489 |
| 2020-04-18 10:08:00 | FSIP1 overexpression correlated with decreased overall survival in hormone receptor-positive breast cancer patients. | 31713931 |
| 2019-02-23 10:57:00 | High FSIP1 expression is associated with drug resistance in triple-negative breast cancer. | 30509973 |
| 2018-06-09 10:04:00 | FSIP1 binds HER2 directly, which regulates breast cancer growth and invasiveness | 28674022 |
| Type | IDs |
|---|---|
| Synonymous | HSD10 |
| Gene |
UniProtKB-ID:
FSIP1_HUMAN,
A0A024R9J2_HUMAN
UniprotKB:
Q8NA03,
A0A024R9J2
UniParc:
UPI000006F96D
EMBL:
AK093308,
CH471125,
BC045191,
AY260140
Ensembl:
ENSG00000150667
KO:
hsa:161835
|
| Nucleutide sequences |
EMBL-CDS:
BAC04128.1,
EAW92382.1,
AAH45191.1,
AAP20066.1,
EAW92383.1
Gene_ORFName:
HSD10,
hCG_38698
Ensembl_TRS:
ENST00000350221
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000280236
RefSeq:
NP_689810.3,
XP_011519613.1,
XP_011519607.1,
XP_011519608.1,
NP_001311267.1,
XP_011519611.1,
XP_011519609.1,
XP_016877461.1
|
| Others |
UniRef100:
UniRef100_Q8NA03
UniRef90:
UniRef90_Q8NA03
UniRef50:
UniRef50_Q8NA03
UniGene:
Hs.129598
CCDS:
CCDS10050.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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