| Type | Description |
|---|---|
| Definition | interleukin-1 receptor-associated kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:48:00 | These findings indicate that BAP31 may modulate inflammatory cytokines and cognitive impairment induced by neuroinflammation through IRAK1 | 31883536 |
| 2019-08-17 10:45:00 | Pharmacological inhibition or siRNA mediated knockdown of IRAK1/4 attenuated Nod1-mediated activation of NF-kappaB, JNK, and the expression of proinflammatory cytokines. These results reveal that Nod1-mediated lipolysis promoted accumulation of DAG, which engaged and IRAK1/4 to augment inflammation in 3T3-L1 adipocytes. | 30391544 |
| 2019-05-25 10:54:00 | IRAK1 is one of the critical components involved in podocyte apoptosis in Diabetic nephropathy. | 30361091 |
| 2018-12-22 10:21:00 | Findings demonstrate that the pro- and anti-inflammatory responses to gAd in innate immune cells are time-dependent, and mediated by the activation of the IkappaB/NF-kappaB pathway, and IRAK-1 downregulation, respectively. | 30078230 |
| 2018-10-27 12:08:00 | suppression of inflammatory responses and T cells apoptosis were observed with elevated expression of IRAK-M and PDL-1, and interference and neutralization of these 2 molecules led to partly reversed suppression of inflammation. | 29995830 |
| Type | IDs |
|---|---|
| Synonymous | AA408924, IRAK, IRAK-1, IRAK1-S, IRAK1b, Il1rak, Plpk, mPLK |
| Gene |
UniProtKB-ID:
IRAK1_MOUSE,
Q540G0_MOUSE,
Q8BR10_MOUSE,
B1AUW6_MOUSE
UniprotKB:
Q62406,
Q540G0,
Q8BR10,
B1AUW6
UniParc:
UPI00000EAE9D,
UPI0000DBEE17,
UPI000005F0A6,
UPI0000029001
EMBL:
AY184363,
AY184364,
AF103876,
U56773,
AK143694,
AL672002,
AY184362,
AK045958
Ensembl:
ENSMUSG00000031392
KO:
mmu:16179
|
| Nucleutide sequences |
EMBL-CDS:
AAC52694.2,
AAO63014.1,
AAD13224.1,
AAO63013.1,
AAO63012.1,
BAE25502.1,
BAC32547.1
Ensembl_TRS:
ENSMUST00000068286,
ENSMUST00000114352,
ENSMUST00000114360,
ENSMUST00000114354,
ENSMUST00000033769
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000064448,
ENSMUSP00000110000,
ENSMUSP00000109992,
ENSMUSP00000109994,
ENSMUSP00000033769
RefSeq:
NP_001171444.1,
NP_032389.2,
NP_001171445.1,
NP_001171446.1,
NP_001171447.1
|
| Others |
UniRef100:
UniRef100_B1AUW6,
UniRef100_Q62406,
UniRef100_Q8BR10
UniRef90:
UniRef90_Q62406-2,
UniRef90_Q62406
UniRef50:
UniRef50_P51617-3,
UniRef50_P51617
UniGene:
Mm.38241
CCDS:
CCDS53103.1,
CCDS30219.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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