| Type | Description |
|---|---|
| Definition | interleukin 1 receptor, type II |
| Date | Results | Publications |
|---|---|---|
| 2019-06-01 11:09:00 | Our studies demonstrate that Zbtb38 forms a molecular bridge between an arthritis-associated epimutation (DNA hypomethylation in Zbtb38 promoter) and transcriptional silencing of the IL1r2 gene in B cells. In this way, disease-associated DNA hypomethylation can support autoimmune arthritis by interfering with an anti-inflammatory pathway. | 30343694 |
| 2019-04-27 10:31:00 | Il1r2 encourages to bind to cis-elements that regulate expression of interleukin-17. | 30093408 |
| 2018-02-24 10:30:00 | Thus, we show that IL-1R2 is harmful for the development of colitis, because IL-1R2 promotes the growth of proinflammatory intestinal microbiota by suppressing IL-1beta-induced AMP production. | 29366788 |
| 2017-09-23 13:54:00 | present study demonstrated the ability of Staphylococcus aureus to induce IL-1RII shedding in myeloid cells | 26967533 |
| 2017-08-19 11:05:00 | Our data demonstrate that the decoy receptor IL-1R2 plays an important inhibitory role in local IL-1- and neutrophil-dependent tissue inflammation | 28235865 |
| Type | IDs |
|---|---|
| Synonymous | CD121b, Il1r-2 |
| Gene |
UniProtKB-ID:
IL1R2_MOUSE,
Q4FK69_MOUSE
UniprotKB:
P27931,
Q4FK69
UniParc:
UPI00000227C1
EMBL:
X59769,
CT010182,
AK132264
Ensembl:
ENSMUSG00000026073
KO:
mmu:16178
|
| Nucleutide sequences |
EMBL-CDS:
CAA42440.1,
CAJ18390.1,
BAE21067.1
Ensembl_TRS:
ENSMUST00000027243
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027243
RefSeq:
NP_001347730.1,
XP_017173211.1,
NP_001347729.1,
XP_006495789.1,
XP_011236740.1,
XP_011236742.1,
XP_036018115.1,
NP_034685.1,
XP_011236739.1,
XP_030106618.1
|
| Others |
UniRef100:
UniRef100_P27931
UniRef90:
UniRef90_P27931
UniRef50:
UniRef50_P27931
UniGene:
Mm.1349
CCDS:
CCDS14909.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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