| Type | Description |
|---|---|
| Definition | sprouty related EVH1 domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:31:00 | Simultaneous Detection of NF1, SPRED1, LZTR1, and NF2 Gene Mutations by Targeted NGS in an Italian Cohort of Suspected NF1 Patients. | 32575496 |
| 2020-06-20 11:07:00 | These data provide structural insight into the interaction of Spred1 and neurofibromin. | 31401120 |
| 2019-08-03 11:56:00 | SPRED1 is down-regulated by E2 and negatively correlated to ER status in BC cells. SPRED1 was a new direct target of miR-196a which participated in miR-196a-promoted BC development and was suppressed by ligand-activated ER-alpha signal pathway. | 29685157 |
| 2019-06-08 11:51:00 | Aberrant methylation statuses of the SPRED1 promoter regions are associated with the downregulation of gene transcription in acute myeloid leukemia. | 30745814 |
| 2019-04-13 10:05:00 | this study establishes SPRED1 as a major tumor suppressor gene in mucosal melanoma. | 30385465 |
| Type | IDs |
|---|---|
| Synonymous | NFLS, PPP1R147, hSpred1, spred-1 |
| Gene |
UniProtKB-ID:
SPRE1_HUMAN
UniprotKB:
Q7Z699
UniParc:
UPI0000072FBD
EMBL:
AY299089,
BC137480,
AK091222,
BC137481,
CH471125,
BC018015
Ensembl:
ENSG00000166068
KO:
hsa:161742
|
| Nucleutide sequences |
EMBL-CDS:
BAC03614.1,
AAI37482.1,
AAH18015.1,
AAI37481.1,
EAW92368.1,
AAP59414.1
Ensembl_TRS:
ENST00000299084
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000299084
RefSeq:
NP_689807.1,
XP_005254259.1,
XP_011519591.1
|
| Others |
UniRef100:
UniRef100_Q7Z699
UniRef90:
UniRef90_Q7Z699
UniRef50:
UniRef50_Q7Z699
UniGene:
Hs.525781
CCDS:
CCDS32193.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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