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16160 Il12b

16160

Il12b

interleukin 12b

protein-coding

Mus musculus

基因描述

Type Description
Definition interleukin 12b

研究结论

Date Results Publications
2020-09-05 13:53:00 Ghrelin effects on mitochondrial fitness modulates macrophage function. 31525456
2020-08-22 15:30:00 Interleukin-12p40 variant form reduces Interleukin-12p80 secretion. 31146247
2020-05-16 10:47:00 Data suggest that 17beta-estradiol induced an immunological response in female bone marrow-derived macrophages resulting in Leishmania mexicana parasite destruction and high production of IL-12p70 and NO synthesis. 31742717
2019-12-07 11:31:00 Donor memory CD8+ T cell activation within allografts subjected to prolonged cold ischemic storage requires memory CD4+ T cell stimulation of graft dendritic cells to produce p40 homodimers, but not IL-12 p40/p35 heterodimers. Targeting p40 abrogates memory CD8+ T cell proliferation within the allografts and their ability to mediate CTLA-4Ig-resistant allograft rejection. 29467328
2019-12-07 10:31:00 IL12p40 depletion promotes the development of abdominal aortic aneurysm, in part, by facilitating recruitment of M2-like macrophages and potentiating aortic stiffness and fibrosis mediated by Tgfbeta2. 30580570

名称对应

Type IDs
Synonymous Il-12b, Il-12p40, Il12p40, p40
Gene
UniProtKB-ID: IL12B_MOUSE, Q3ZAX5_MOUSE
UniprotKB: P43432, Q3ZAX5
UniParc: UPI00000284CA
EMBL: AF128214, BC103610, BC103608, AK162981, AF128215, BC103609, BC103614, S82422, S82421, S82425, M86671, S82426, S82424
Ensembl: ENSMUSG00000004296
KO: mmu:16160
Nucleutide sequences
EMBL-CDS: AAA39296.1, AAB37383.1, AAF22555.1, AAF22556.1, BAE37146.1, AAI03609.1, AAI03615.1, AAI03610.1, AAI03611.1
Ensembl_TRS: ENSMUST00000102796, ENSMUST00000170513
Protein sequencees
Ensembl_PRO: ENSMUSP00000125867, ENSMUSP00000099860
RefSeq: NP_001290173.1
Others
UniRef100: UniRef100_P43432
UniRef90: UniRef90_P43432
UniRef50: UniRef50_P29460
UniGene: Mm.239707
CCDS: CCDS24563.1

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