| Type | Description |
|---|---|
| Definition | interleukin 12a |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:44:00 | Induced and spontaneous colitis mouse models reveal complex interactions between IL-10 and IL-12/IL-23 pathways. | 31158699 |
| 2020-05-23 10:34:00 | IL-12p35 knockout amplifies the inflammatory response and promotes blood pressure elevation in Ang II-treated mice. | 30395167 |
| 2020-05-16 10:47:00 | Data suggest that 17beta-estradiol induced an immunological response in female bone marrow-derived macrophages resulting in Leishmania mexicana parasite destruction and high production of IL-12p70 and NO synthesis. | 31742717 |
| 2020-02-15 10:13:00 | IL-35 subunits (EBI3 and p35), which are mainly expressed in regulatory T cells, were upregulated in mice after myocardial infarction. IL-35 reduces cardiac rupture, improves wound healing, and attenuates cardiac remodeling after MI by promoting reparative CX3CR1(+)Ly6C(low) macrophage survival. | 30832557 |
| 2019-08-03 12:31:00 | Our study demonstrates that in dendritic cells infected with Lymphocytic choriomeningitis virus, TLR activation with bacterial PAMPs resulted in reduced IL-12 and IL-23 expression compared to non-infected cells. | 29602153 |
| Type | IDs |
|---|---|
| Synonymous | IL-12p35, Il-12a, Ll12a, p35 |
| Gene |
UniProtKB-ID:
IL12A_MOUSE,
F8WI71_MOUSE,
Q549G3_MOUSE
UniprotKB:
P43431,
F8WI71,
Q549G3
UniParc:
UPI00019A9EE5,
UPI0000000291
EMBL:
D63334,
BC116851,
AF128213,
S82419,
S82417,
AF128212,
S82412,
M86672,
S82418,
BC116855,
S82414,
AC121306
Ensembl:
ENSMUSG00000027776
KO:
mmu:16159
|
| Nucleutide sequences |
EMBL-CDS:
AAA39292.1,
BAA09647.1,
AAB37382.1,
AAI16856.1,
AAF22553.1,
AAI16852.1,
AAF22554.1
Ensembl_TRS:
ENSMUST00000107816,
ENSMUST00000029345
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103446,
ENSMUSP00000029345
RefSeq:
NP_001152896.1,
XP_006501107.1,
NP_032377.1
|
| Others |
UniRef100:
UniRef100_P43431
UniRef90:
UniRef90_P43431
UniRef50:
UniRef50_P43431
UniGene:
Mm.103783
CCDS:
CCDS17400.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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