| Type | Description |
|---|---|
| Definition | inhibitor of kappaB kinase gamma |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:25:00 | N4BP1 negatively regulates NF-kappaB by binding and inhibiting NEMO oligomerization. | 33654074 |
| 2021-02-06 13:56:00 | SENP1-mediated NEMO de-SUMOylation inhibits intermittent hypoxia induced inflammatory response of microglia in vitro. | 31549402 |
| 2020-10-24 14:09:00 | DNA-PK: gatekeeper for IKKgamma/NEMO nucleocytoplasmic shuttling in genotoxic stress-induced NF-kappaB activation. | 31932854 |
| 2020-07-18 12:43:00 | The murine cytomegalovirus (Murid herpesvirus 1) M45 protein induces the degradation of two cellular signalling proteins, the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) essential modulator (NEMO) and the receptor-interacting protein kinase 1 (RIPK1), via a different mechanism: it induces their sequestration as insoluble protein aggregates and subsequently facilitates their degradation by... | 31844296 |
| 2020-03-28 10:28:00 | Data show that mitochondrial reactive oxygen species disulfide linkage of NF-KappaB essential modulator (NEMO) as an essential regulatory step of the proinflammatory response of macrophages to bacterial infection. | 30755476 |
| Type | IDs |
|---|---|
| Synonymous | 1110037D23Rik, AI848108, AI851264, AW124339, IKK[g], NEMO |
| Gene |
UniProtKB-ID:
NEMO_MOUSE,
E9Q2Y3_MOUSE,
Q8VC91_MOUSE,
Q7TSS3_MOUSE
UniprotKB:
O88522,
E9Q2Y3,
Q8VC91,
Q7TSS3
UniParc:
UPI00001A32A0,
UPI000047BF58,
UPI0000020DD8,
UPI00000E88F8
EMBL:
AF326207,
AK037020,
AL669976,
BC021431,
AF513109,
AF069542,
AL807376,
AK154095,
AY112937,
CH466650
Ensembl:
ENSMUSG00000004221
KO:
mmu:16151
|
| Nucleutide sequences |
EMBL-CDS:
EDL29810.1,
BAE32372.1,
AAP47160.1,
AAK69186.1,
AAC40153.1,
AAH21431.1,
BAC29672.1,
AAM54725.1
Ensembl_TRS:
ENSMUST00000114127,
ENSMUST00000114128,
ENSMUST00000114133,
ENSMUST00000164101,
ENSMUST00000114130,
ENSMUST00000064407,
ENSMUST00000180230,
ENSMUST00000114129,
ENSMUST00000004330
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109762,
ENSMUSP00000109763,
ENSMUSP00000126770,
ENSMUSP00000109768,
ENSMUSP00000109765,
ENSMUSP00000136573,
ENSMUSP00000064017,
ENSMUSP00000109764,
ENSMUSP00000004330
RefSeq:
NP_001154893.1,
XP_006527910.1,
NP_001154896.1,
NP_001154895.1,
NP_848705.1,
XP_006527911.1,
NP_001129539.1,
XP_006527912.1,
XP_006527916.1,
XP_006527914.1,
XP_006527915.1,
NP_034677.2,
XP_011245829.1,
NP_001154894.1,
XP_006527913.1
|
| Others |
UniRef100:
UniRef100_Q8VC91,
UniRef100_E9Q2Y3,
UniRef100_O88522
UniRef90:
UniRef90_O88522
UniRef50:
UniRef50_O88522
UniGene:
Mm.12967
CCDS:
CCDS41023.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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