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16149 Cd74

16149

Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

protein-coding

Mus musculus

基因描述

Type Description
Definition CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

研究结论

Date Results Publications
2020-10-03 12:58:00 Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling. 31669150
2020-05-09 13:28:00 CD74 knockout protects against ethanol-induced alterations in autophagy, AMPK hyperphosphorylation and mTOR dephosphorylation. The permissive role for Sirt1 in CD74 ablation-offered beneficial responses in autophagy and cardiac function against ethanol received consolidation from the SRT1720-induced removal of CD74 knockout-induced contractile and autophagy benefits. 31167126
2019-10-12 10:30:00 The amount of soluble MHC class II molecules in serum was decreased in Invariant chain (Ii), also called CD74, -deficient mice compared to wild-type mice. 30587340
2019-04-20 12:42:00 TWEAK upregulates CD74 and its ligands MIF and DDT in renal tubular cells. 29924850
2018-01-20 12:06:00 House dust mites sensitization lowered humoral immune responses to intact pneumococcus and this effect was significantly modified by the HLA-DR polymorphism. 27506953

名称对应

Type IDs
Synonymous CLIP, DHLAG, HLADG, Ia-GAMMA, Ii
Gene
UniProtKB-ID: HG2A_MOUSE, Q3U4Q8_MOUSE, Q545Y5_MOUSE
UniprotKB: P04441, Q3U4Q8, Q545Y5
UniParc: UPI0000001849, UPI0000003E32
EMBL: X05430, M35872, BC003476, X00496, X07129, X05428, AK002232, X05429, X13414, BC096435, AK154096
Ensembl: ENSMUSG00000024610
KO: mmu:16149
Nucleutide sequences
EMBL-CDS: CAA29010.1, AAH03476.1, AAA37897.1, CAB37297.1, CAA29012.2, CAA30141.1, CAA25191.1, BAE32373.1, BAB21951.1, AAH96435.1
Ensembl_TRS: ENSMUST00000167610, ENSMUST00000050487, ENSMUST00000097563
Protein sequencees
Ensembl_PRO: ENSMUSP00000057836, ENSMUSP00000095171, ENSMUSP00000126688
RefSeq: NP_001036070.1, NP_034675.1
Others
UniRef100: UniRef100_Q545Y5, UniRef100_P04441
UniRef90: UniRef90_Q545Y5, UniRef90_P04441
UniRef50: UniRef50_P04441, UniRef50_P04233-2
UniGene: Mm.439737
CCDS: CCDS50299.1, CCDS37835.1

全选

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