| Type | Description |
|---|---|
| Definition | interferon gamma induced GTPase |
| Date | Results | Publications |
|---|---|---|
| 2015-07-25 11:10:00 | protection from experimental cerebral malaria pathology in Irgm3-/- mice occurs due to impaired generation of CD8+ effector function. This defect is nonintrinsic to CD8+ T cells. | 25644000 |
| 2014-01-18 10:04:00 | the paralogous IRGM proteins Irgm1 and Irgm3 fail to robustly associate with "non-self" PVs containing either the bacterial pathogen Chlamydia trachomatis or the protozoan pathogen Toxoplasma gondii | 23785284 |
| 2011-10-29 10:21:00 | IRGM proteins indirectly modulate the localization of GBP2 through a distinct mechanism from that through which they regulate IRG protein localization | 21757726 |
| 2011-10-22 10:24:00 | Data show that hyperproliferation, self-renewal, and autophagy defects in Irgm1(-/-) HSCs were normalized in double-knockout Irgm1(-/-)Ifngr1(-/-) and Irgm1(-/-)Stat1(-/-), and the defects were abolished in Irgm1(-/-)Irgm3(-/-) double-knockout. | 21633090 |
| 2010-03-15 12:09:00 | IFN-gamma-inducible signaling has pleiotropic effects on immune defense and revealing that p47 GTPases function differentially depending on invading pathogen species. | 20029464 |
| Type | IDs |
|---|---|
| Synonymous | AW558444, Irgm3 |
| Gene |
UniProtKB-ID:
Q9DCE9_MOUSE
UniprotKB:
Q9DCE9
UniParc:
UPI0000028590
EMBL:
AL928857,
AK149817,
AK002843,
AK151860,
AK152483,
AK169307,
AK151779
Ensembl:
ENSMUSG00000078853
KO:
mmu:16145
|
| Nucleutide sequences |
EMBL-CDS:
BAE31255.1,
BAE29102.1,
BAE30749.1,
BAE30684.1,
BAE41062.1,
BAB22400.1
Ensembl_TRS:
ENSMUST00000035266
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047356
RefSeq:
NP_061208.3
|
| Others |
UniRef100:
UniRef100_Q9DCE9
UniRef90:
UniRef90_Q9DCE9
UniRef50:
UniRef50_Q9DCE9
UniGene:
Mm.33902
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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