| Type | Description |
|---|---|
| Definition | death associated protein |
| Date | Results | Publications |
|---|---|---|
| 2015-12-05 11:43:00 | DAP1 may have an important role in cell adhesion, migration and growth in the context of breast cancer and has significant associations with the apoptosis pathway. | 25530065 |
| 2014-09-06 10:17:00 | DAP1 was found to be correlated with disease progression and long-term survival of the colorectal patients. DAP1 is also a pivotal regulator of the growth and apoptosis and cellular response to chemotherapy agents. | 24270644 |
| 2013-11-21 17:24:00 | This study demonstrates an inverse association between DAP1 mRNA levels and tumour stage and clinical outcome in breast cancer | 22798505 |
| 2013-11-21 17:22:00 | Mapping of the phosphorylation sites and analysis of phosphorylation mutants indicated that DAP1 is functionally silenced in growing cells through mTOR-dependent phosphorylations on Ser3 and Ser51 | 20537536 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
DAP1_HUMAN,
B4DQ75_HUMAN
UniprotKB:
P51397,
B4DQ75
UniParc:
UPI00017A7947,
UPI0000128E2E
EMBL:
BC002726,
X76105,
AK298670,
AY266680,
AC012629,
CR542184
Ensembl:
ENSG00000112977
KO:
hsa:1611
|
| Nucleutide sequences |
EMBL-CDS:
CAA53713.1,
CAG46981.1,
AAH02726.2,
AAO89078.1,
BAG60837.1
Ensembl_TRS:
ENST00000230895,
ENST00000432074
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000230895,
ENSP00000394163
RefSeq:
NP_001278892.1,
NP_004385.1
|
| Others |
UniRef100:
UniRef100_P51397,
UniRef100_B4DQ75
UniRef90:
UniRef90_P51397,
UniRef90_A0A2I2ZR66
UniRef50:
UniRef50_A0A2I2ZR66,
UniRef50_P51397
UniGene:
Hs.75189
CCDS:
CCDS3880.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 25530065 |
Oncol. Rep. Umar Wazir , Andrew J Sanders , Ali Wazir , Ruqia Mehmood Baig , Wen G Jiang , Irina C Ster , Anup K Sharma , Kefah Mokbel |
2015-03-01 |
DAP
|
| 24270644 |
Oncol. Rep. Yongning Jia , Lin Ye , Ke Ji , Ann-Marie Toms , Mansel Leigh Davies , Fiona Ruge , Jiafu Ji , Rachel Hargest , Wen G Jiang |
2014-01-01 |
DAP
|
| 23934736 |
Genet. Epidemiol. Bing Yu , Yan Zheng , Danny Alexander , Teri A Manolio , Alvaro Alonso , Jennifer A Nettleton , Eric Boerwinkle |
2013-12-01 |
LOC100130177,
CDH4,
ZNF213-AS1,
CDKN3,
SORCS1,
SLC44A3,
CNTN1,
LRRIQ3,
ISM1,
APCDD1,
LOC149844,
DAB2IP,
DGKH,
DAP,
AAK1,
ANKRD6,
ADGRL2,
KIF13B,
DKK3,
TUSC1,
CTNNA3,
GTF2E2,
TRHDE,
NRG1,
ICA1,
EYS,
PSIP1P1,
CYCSP8,
CCDC178,
C9orf50,
C15orf54,
MGMT,
MYO5A,
NUP98,
MS4A13,
COMMD10,
BNC2,
PRKCE,
CCL28,
RELN,
PRTFDC1,
PVT1,
KC6,
SHB,
SLC12A1,
TPD52,
FAM155A,
LOC729217,
ZNF213,
CACNA2D1,
ALMS1,
CDK5RAP3,
SLCO5A1,
CADPS,
NAT8,
PSMD6
|
| 23128233 |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature Luke Jostins , Stephan Ripke , Rinse K Weersma , Richard H Duerr , Dermot P McGovern , Ken Y Hui , James C Lee , L Philip Schumm , Yashoda Sharma , Carl A Anderson , Jonah Essers , Mitja Mitrovic , Kaida Ning , Isabelle Cleynen , Emilie Theatre , Sarah L Spain , Soumya Raychaudhuri , Philippe Goyette , Zhi Wei , Clara Abraham , Jean-Paul Achkar , Tariq Ahmad , Leila Amininejad , Ashwin N Ananthakrishnan , Vibeke Andersen , Jane M Andrews , Leonard Baidoo , Tobias Balschun , Peter A Bampton , Alain Bitton , Gabrielle Boucher , Stephan Brand , Carsten Büning , Ariella Cohain , Sven Cichon , Mauro D'Amato , Dirk De Jong , Kathy L Devaney , Marla Dubinsky , Cathryn Edwards , David Ellinghaus , Lynnette R Ferguson , Denis Franchimont , Karin Fransen , Richard Gearry , Michel Georges , Christian Gieger , Jürgen Glas , Talin Haritunians , Ailsa Hart , Chris Hawkey , Matija Hedl , Xinli Hu , Tom H Karlsen , Limas Kupcinskas , Subra Kugathasan , Anna Latiano , Debby Laukens , Ian C Lawrance , Charlie W Lees , Edouard Louis , Gillian Mahy , John Mansfield , Angharad R Morgan , Craig Mowat , William Newman , Orazio Palmieri , Cyriel Y Ponsioen , Uros Potocnik , Natalie J Prescott , Miguel Regueiro , Jerome I Rotter , Richard K Russell , Jeremy D Sanderson , Miquel Sans , Jack Satsangi , Stefan Schreiber , Lisa A Simms , Jurgita Sventoraityte , Stephan R Targan , Kent D Taylor , Mark Tremelling , Hein W Verspaget , Martine De Vos , Cisca Wijmenga , David C Wilson , Juliane Winkelmann , Ramnik J Xavier , Sebastian Zeissig , Bin Zhang , Clarence K Zhang , Hongyu Zhao , International IBD Genetics Consortium (IIBDGC) , Mark S Silverberg , Vito Annese , Hakon Hakonarson , Steven R Brant , Graham Radford-Smith , Christopher G Mathew , John D Rioux , Eric E Schadt , Mark J Daly , Andre Franke , Miles Parkes , Severine Vermeire , Jeffrey C Barrett , Judy H Cho |
2012-11-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21297633 |
Nat. Genet. Carl A Anderson , Gabrielle Boucher , Charlie W Lees , Andre Franke , Mauro D'Amato , Kent D Taylor , James C Lee , Philippe Goyette , Marcin Imielinski , Anna Latiano , Caroline Lagacé , Regan Scott , Leila Amininejad , Suzannah Bumpstead , Leonard Baidoo , Robert N Baldassano , Murray Barclay , Theodore M Bayless , Stephan Brand , Carsten Büning , Jean-Frédéric Colombel , Lee A Denson , Martine De Vos , Marla Dubinsky , Cathryn Edwards , David Ellinghaus , Rudolf S N Fehrmann , James A B Floyd , Timothy Florin , Denis Franchimont , Lude Franke , Michel Georges , Jürgen Glas , Nicole L Glazer , Stephen L Guthery , Talin Haritunians , Nicholas K Hayward , Jean-Pierre Hugot , Gilles Jobin , Debby Laukens , Ian Lawrance , Marc Lémann , Arie Levine , Cecile Libioulle , Edouard Louis , Dermot P McGovern , Monica Milla , Grant W Montgomery , Katherine I Morley , Craig Mowat , Aylwin Ng , William Newman , Roel A Ophoff , Laura Papi , Orazio Palmieri , Laurent Peyrin-Biroulet , Julián Panés , Anne Phillips , Natalie J Prescott , Deborah D Proctor , Rebecca Roberts , Richard Russell , Paul Rutgeerts , Jeremy Sanderson , Miquel Sans , Philip Schumm , Frank Seibold , Yashoda Sharma , Lisa A Simms , Mark Seielstad , A Hillary Steinhart , Stephan R Targan , Leonard H van den Berg , Morten Vatn , Hein Verspaget , Thomas Walters , Cisca Wijmenga , David C Wilson , Harm-Jan Westra , Ramnik J Xavier , Zhen Z Zhao , Cyriel Y Ponsioen , Vibeke Andersen , Leif Torkvist , Maria Gazouli , Nicholas P Anagnou , Tom H Karlsen , Limas Kupcinskas , Jurgita Sventoraityte , John C Mansfield , Subra Kugathasan , Mark S Silverberg , Jonas Halfvarson , Jerome I Rotter , Christopher G Mathew , Anne M Griffiths , Richard Gearry , Tariq Ahmad , Steven R Brant , Mathias Chamaillard , Jack Satsangi , Judy H Cho , Stefan Schreiber , Mark J Daly , Jeffrey C Barrett , Miles Parkes , Vito Annese , Hakon Hakonarson , Graham Radford-Smith , Richard H Duerr , Séverine Vermeire , Rinse K Weersma , John D Rioux |
2011-03-01 | - |
| 20537536 |
DAP1, a novel substrate of mTOR, negatively regulates autophagy. Curr. Biol. Itay Koren , Eran Reem , Adi Kimchi |
2010-06-22 |
DAP,
EIF4EBP1,
MTOR,
SUMO1
|
| 20237496 |
New genetic associations detected in a host response study to hepatitis B vaccine. Genes Immun. S Davila , F E M Froeling , A Tan , C Bonnard , G J Boland , H Snippe , M L Hibberd , M Seielstad |
2010-04-01 |
SH2B3,
MICA,
NR1H3,
TSPAN2,
NAMPT,
PRG4,
KLRG1,
CD96,
EFS,
APC2,
LAMC3,
CRISP3,
TLR6,
CLEC10A,
SEMA4D,
CEBPG,
PROCR,
PRDX4,
IFI44,
CXCL13,
GNLY,
COLEC10,
SH2B2,
CD226,
TNFSF13B,
NFAT5,
KLRA1P,
CFHR4,
CFHR3,
C1QL1,
EDAR,
MAGED2,
PRDX3,
IFI44L,
LILRB5,
LILRB4,
LILRA1,
LILRA2,
DUS4L,
ESM1,
FGFR1OP,
FAF1,
CD160,
RASSF1,
IRAK3,
IL17F,
CHRM1,
CD300A,
COPE,
KIF12,
CMTM1,
SIGLEC11,
NLRP3,
TIRAP,
PGLYRP2,
PGLYRP3,
SLAMF6,
FCRL1,
FCRL3,
GBP4,
GBP5,
TNFRSF13C,
FOXP4,
IL22RA2,
DEFB118,
CLC,
ADD1,
SFXN4,
IFI27L1,
CCR3,
CCR4,
CCR5,
CCR7,
CCR8,
ACKR2,
CMKLR1,
CCDC78,
CD300LB,
OSCAR,
ANKLE1,
GABPB2,
CNTFR,
COL4A3,
COL4A4,
BPIFB6,
ZPLD1,
KLF6,
IL31RA,
PPARGC1B,
RAET1E,
ADORA2B,
SSC4D,
CR1,
PXDNL,
CR2,
CREB1,
CREM,
GAB3,
CRP
|
| 20379614 |
Mol. Med. Jed E Rose , Frédérique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl |
2010-03-17 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员