DGKH - diacylglycerol kinase eta-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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160851 DGKH

基因描述

Type	Description
Definition	diacylglycerol kinase eta

研究结论

Date	Results	Publications
2019-01-26 12:26:00	The present study shows that a bipolar-risk allele of DGKH is associated with higher openness to experience, providing further evidence for the implication of this gene in the etiology of bipolar disorder.	29936393
2018-02-03 10:31:00	This sstudy shown that the highest expression levels of DGKH in the human brain were found in the striatum.	27085324
2017-11-25 16:00:00	DGKH is a replicated risk gene of bipolar disorder (BD).	27016658
2017-09-23 12:32:00	several single variants and genes showed strong association with Panic Disorders, where DGKH was found to be the strongest Panic Disorder associated gene. Interestingly DGKH has previously demonstrated genome-wide significant association with bipolar disorder as well as evidence of association to other mental disorders.	27255576
2016-09-03 10:58:00	DGKeta-Pleckstrin Homology Domain preferentially interacts with Phosphatidylinositol 4,5-Bisphosphate and has crucial roles in regulating the subcellular localization and physiological function of DGKeta.	26887948

名称对应

Type	IDs
Synonymous	DGKeta
Gene	UniProtKB-ID: DGKH_HUMAN, A8K0I1_HUMAN, B4DYW1_HUMAN UniprotKB: Q86XP1, A8K0I1, B4DYW1 UniParc: UPI00017A8430, UPI00015DA469, UPI00017A8557, UPI000017DA47, UPI00001BDB24, UPI000003C97D EMBL: AK098302, AB078967, AK302631, AK302727, AB078968, AL157932, BC043292, AL833883, AL139328, AK289546, AL136527 Ensembl: ENSG00000102780 KO: hsa:160851
Nucleutide sequences	EMBL-CDS: CAD38739.1, AAH43292.1, BAC66961.1, BAC05280.1, BAG63946.1, BAC66960.1, BAF82235.1, BAG63873.1 Ensembl_TRS: ENST00000261491, ENST00000536612, ENST00000379274, ENST00000628433, ENST00000337343
Protein sequencees	Ensembl_PRO: ENSP00000485809, ENSP00000368576, ENSP00000445114, ENSP00000337572, ENSP00000261491 RefSeq: NP_001284358.1, NP_001191433.1, NP_821077.1, NP_690874.2, NP_001191435.1, NP_001191434.1
Others	UniRef100: UniRef100_Q86XP1, UniRef100_B4DYW1, UniRef100_A8K0I1 UniRef90: UniRef90_Q86XP1, UniRef90_A0A1S3G6N2 UniRef50: UniRef50_A0A1S3G6N2, UniRef50_Q86XP1 UniGene: Hs.733239 CCDS: CCDS55898.1, CCDS55899.1, CCDS9381.1, CCDS9382.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32877691	A High-Density Human Mitochondrial Proximity Interaction Network. Cell Metab Hana Antonicka , Zhen-Yuan Lin , Alexandre Janer , Mari J Aaltonen , Woranontee Weraarpachai , Anne-Claude Gingras , Eric A Shoubridge	2020-09-01	-
30021884	Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. Mol Cell Proteomics Domenico Fasci , Hugo van Ingen , Richard A Scheltema , Albert J R Heck	2018-10-01	-
29936393	Implication of the DGKH genotype in openness to experience, a premorbid personality trait of bipolar disorder. J Affect Disord Yoshihiko Matsumoto , Akihito Suzuki , Toshinori Shirata , Nana Takahashi , Keisuke Noto , Kaoru Goto , Koichi Otani	2018-10-01	-
29987050	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proc. Natl. Acad. Sci. U.S.A. Tengfei Xiao , Wei Li , Xiaoqing Wang , Han Xu , Jixin Yang , Qiu Wu , Ying Huang , Joseph Geradts , Peng Jiang , Teng Fei , David Chi , Chongzhi Zang , Qi Liao , Jonathan Rennhack , Eran Andrechek , Nanlin Li , Simone Detre , Mitchell Dowsett , Rinath M Jeselsohn , X Shirley Liu , Myles Brown	2018-07-31	-
29676528	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. FEBS J. Richa Khanna , Vidhya Krishnamoorthy , Veena K Parnaik	2018-06-01	-
29507755	VIRMA mediates preferential m⁶A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu	2018-01-01	-
27085324	Expressional profile of the diacylglycerol kinase eta gene DGKH. Eur Arch Psychiatry Clin Neurosci Lena WeiÃflog , Nils Becker , Nelli Bossert , Florian Freudenberg , Sarah Kittel-Schneider , Andreas Reif	2017-08-01	-
28611215	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown	2017-06-27	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
27255576	Whole-exome sequencing implicates DGKH as a risk gene for panic disorder in the Faroese population. Am J Med Genet B Neuropsychiatr Genet Noomi O Gregersen , Francesco Lescai , Jieqin Liang , Qibin Li , Thomas Als , Henriette N ButtenschÃ¸n , Anne Hedemand , Marjun BiskopstÃ¸ , Jun Wang , August G Wang , Anders D BÃ¸rglum , Ole Mors , Ditte Demontis	2016-12-01	-

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