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160622 GRASP

160622

GRASP

general receptor for phosphoinositides 1 associated scaffold protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition general receptor for phosphoinositides 1 associated scaffold protein

研究结论

Date Results Publications
2021-01-09 13:28:00 The post-synaptic scaffolding protein tamalin regulates ligand-mediated trafficking of metabotropic glutamate receptors. 32376687
2016-05-07 11:25:00 Schizophrenia subjects compared to controls showed a marked increase in CA1 hippocampal Norbin, and Tamalin proteins (47% and 34% respectively), which are endogenous regulators of mGluR5 signalling and trafficking 26048293
2014-05-31 11:48:00 myristoylated GRASP promoted tethering and exhibited a unique membrane complex. Thus, myristoylation restricts the membrane orientation of the GRASP domain favoring interactions in trans for membrane tethering. 24505136
2013-06-29 11:28:00 GRASP bridges the guanine nucleotide exchange factors (GEFs) that activate Arf and Rac, thereby promoting Arf-to-Rac signaling By binding to both cytohesin 2/ARNO and Dock180. 23441967
2013-04-27 11:13:00 GRASP regulates the non-clathrin/Arf6-dependent, plasma membrane recycling and signalling pathways. 22931251

名称对应

Type IDs
Synonymous TAMALIN
Gene
UniProtKB-ID: GRASP_HUMAN
UniprotKB: Q7Z6J2
UniParc: UPI00001A9479, UPI00001BDAF5
EMBL: BC053666, BC052967, BC035500
Ensembl: ENSG00000161835
KO: hsa:160622
Nucleutide sequences
EMBL-CDS: AAH35500.1, AAH52967.1, AAH53666.1
Ensembl_TRS: ENST00000552049, ENST00000293662
Protein sequencees
Ensembl_PRO: ENSP00000449492, ENSP00000293662
RefSeq: XP_005268748.1, NP_859062.1, XP_011536298.1, NP_001258785.1
Others
UniRef100: UniRef100_Q7Z6J2
UniRef90: UniRef90_Q7Z6J2
UniRef50: UniRef50_Q7Z6J2
UniGene: Hs.407202
CCDS: CCDS61124.1, CCDS8817.1

全选

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研究热度

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