| Type | Description |
|---|---|
| Definition | insulin-like growth factor binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-21 12:04:00 | In inflamed experimental autoimmune encephalomyelitis (EAE) spinal cord, study found a significant increased number of IGF-I expressing neurons versus a reduced number of IGFBP-1 positive neurons. Moreover, while nearly all IGF-I neurons expressed GSK3beta, some expressed it more intensely. | 28617951 |
| 2016-09-10 11:26:00 | the hepatokine IGFBP1 is a critical liver-bone hormonal relay that promotes osteoclastogenesis and bone resorption as well as an essential mediator of FGF21-induced bone loss | 26456333 |
| 2015-08-15 11:25:00 | Data suggest expression of Igfbp1 in liver is regulated by dietary factors; carnosine supplementation down-regulates expression of Igfbp1 in liver of obese/diabetic mice; mechanism involves suppression of Hif1a (hypoxia inducible factor 1 alpha). | 25869614 |
| 2014-09-27 10:53:00 | serum IGFBPI protein could provide an easily measured biomarker for early detection of alcohol-induced liver injury in humans | 24152801 |
| 2013-07-20 12:10:00 | During the two week starvation period, both the levels of plasma IGF-1 and IGFBP-1 decreased. | 22653858 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IBP1_MOUSE
UniprotKB:
P47876
UniParc:
UPI0000192B43
EMBL:
AL607124,
X81579,
CH466574,
X67493
Ensembl:
ENSMUSG00000020429
KO:
mmu:16006
|
| Nucleutide sequences |
EMBL-CDS:
CAA47832.1,
CAA57269.1,
EDL40608.1
Ensembl_TRS:
ENSMUST00000020704
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020704
RefSeq:
NP_032367.3
|
| Others |
UniRef100:
UniRef100_P47876
UniRef90:
UniRef90_P21743
UniRef50:
UniRef50_P21743
UniGene:
Mm.21300
CCDS:
CCDS24427.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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