| Type | Description |
|---|---|
| Definition | DAB adaptor protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 12:40:00 | Our study strongly suggests that Dab1 may be a potential tumour suppressor gene in breast cancer. | 30484953 |
| 2020-04-04 10:54:00 | The appearance of DAB1 and Reelin during fetal kidney development confirms their potential significant role in the formation of kidney structure or function. High DAB1 expression in the DCT implies its regulatory role in tubular formation or function maintenance during development. | 31894918 |
| 2019-08-17 10:42:00 | our findings provide direct evidence for the impaired Reelin-DAB1 transduction cascade in a patient with deleterious variants in the RELN gene, suggest, for the first time, an abnormal interplay between Reelin-DAB1 and mTORC1 signaling pathways in a patient with nonsyndromic ASD | 29969175 |
| 2018-09-08 12:01:00 | In intestine a truncated Dab1 variant transmits the reelin signal and may play a role in clathrin-mediated apical endocytosis and in the control of cell-to-cell junction assembly. Dab1 variant may be a nucleocytoplasmic shuttling protein, inferred from its sequence and nuclear location. | 29470947 |
| 2017-08-05 10:11:00 | these results establish an unstable repeat insertion in DAB1 as a cause of cerebellar degeneration. | 28686858 |
| Type | IDs |
|---|---|
| Synonymous | SCA37 |
| Gene |
UniProtKB-ID:
DAB1_HUMAN
UniprotKB:
O75553
UniParc:
UPI000153BFAA,
UPI000013EE33,
UPI0000204438,
UPI0000350B4A,
UPI000040DC2E,
UPI0000470B70
EMBL:
BC112938,
AL139219,
BC067445,
AK095513,
AF263547,
AL354883,
BC067446,
AL161740,
BC067447,
AF071062,
CH471059,
AB210012
Ensembl:
ENSG00000173406
KO:
hsa:1600
|
| Nucleutide sequences |
EMBL-CDS:
AAH67447.1,
BAG53075.1,
EAX06637.1,
BAE06094.1,
AAF73058.1,
AAH67445.1,
AAI12939.1,
AAH67446.1,
AAC70068.1
Ensembl_TRS:
ENST00000371236,
ENST00000371230,
ENST00000420954,
ENST00000414851,
ENST00000371231
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360275,
ENSP00000395296,
ENSP00000360274,
ENSP00000360280,
ENSP00000387581
RefSeq:
NP_001352723.1,
NP_001366391.1,
NP_001352721.1,
NP_001340912.1,
NP_001340914.1,
NP_001352722.1,
NP_001340915.1,
NP_066566.3,
NP_001352724.1,
NP_001366390.1,
NP_001340909.1
|
| Others |
UniRef100:
UniRef100_O75553
UniRef90:
UniRef90_O75553
UniRef50:
UniRef50_O75553
UniGene:
Hs.477370
CCDS:
CCDS607.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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