| Type | Description |
|---|---|
| Definition | interferon-induced protein with tetratricopeptide repeats 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 10:03:00 | PolyI:C stimulated BMM of Tlr3(-/-) mice showed a reduction of Ifit1 (p=0.003) and Mx1 (p<0.0001) mRNA compared to control. We here demonstrate that TLR3 can play a protective role in VGD development, possibly regulated via type-I IFNs and a reduced inflammatory response. | 29879406 |
| 2018-12-29 10:42:00 | ISG20 acts as an indirect regulator of RNA virus replication in the cytoplasm through the upregulation of many other ISGs. | 30232164 |
| 2018-03-03 11:20:00 | IFIT1 expression is associated with podocytes damage, and capable of suppressing some proteins essential to glomerular filtration. | 27823966 |
| 2017-11-26 01:15:00 | Human IFIT1 and mouse IFIT1 have divergent antiviral specificities: only IFIT1 proteins inhibit a virus encoding a cap 2'O-methyltransferase. | 27240734 |
| 2016-11-12 11:24:00 | the mechanism for the observed differential induction of the mouse Ifit1, Ifit2, and Ifit3 genes in B cells and demonstrated that the repressive effect of the transcription factor interferon regulatory factor 8 (IRF8), which is highly expressed in B cells, played an essential role in this regulation. | 27137933 |
| Type | IDs |
|---|---|
| Synonymous | ISG56, Ifi56, P56 |
| Gene |
UniProtKB-ID:
IFIT1_MOUSE
UniprotKB:
Q64282
UniParc:
UPI00000E7D5B
EMBL:
AK151298,
AK150424,
AK151158,
AK150352,
S77715,
AK151125,
AK157848,
BC003768,
AK153184,
AK150609,
S77714,
CH466534,
CT010226,
U43084,
AK151278
Ensembl:
ENSMUSG00000034459
KO:
mmu:15957
|
| Nucleutide sequences |
EMBL-CDS:
BAE30265.1,
AAC52625.1,
BAE29489.1,
CAJ18434.1,
BAE29700.1,
BAE31785.1,
BAE34228.1,
AAB33831.2,
BAE30133.1,
BAE29547.1,
BAE30281.1,
EDL41756.1,
AAH03768.1,
BAE30163.1
Ensembl_TRS:
ENSMUST00000102824
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099888
RefSeq:
NP_032357.2
|
| Others |
UniRef100:
UniRef100_Q64282
UniRef90:
UniRef90_Q64282
UniRef50:
UniRef50_P09914
UniGene:
Mm.439751
CCDS:
CCDS29766.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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