| Type | Description |
|---|---|
| Definition | cytochrome P450 family 51 subfamily A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | A requirement for an active proton delivery network supports a compound I-mediated C-C bond cleavage in CYP51 catalysis. | 32493730 |
| 2020-07-04 11:45:00 | the E3 ubiquitin ligase membrane-associated ring-CH-type finger 6 (MARCH6), known to control earlier rate-limiting steps in cholesterol synthesis, also control levels of LDM and the terminal cholesterol synthesis enzyme, 24-dehydrocholesterol reductase. | 31904814 |
| 2019-05-18 12:18:00 | Analysis of molecular docking data demonstrated the ability of abiraterone and galeterone to bind to the active site of CYP51A1, but abiraterone occupies the position closer to the heme. | 29807244 |
| 2017-09-30 12:14:00 | the regulation of expression of human CYP51A1, the lanosterol 14alpha-demethylase, is reported. | 28830911 |
| 2017-09-09 11:03:00 | Molecular insights regarding substrate profile, faster catalysis, and weaker susceptibility of human CYP51 to inhibition. | 27313059 |
| Type | IDs |
|---|---|
| Synonymous | CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1 |
| Gene |
UniProtKB-ID:
CP51A_HUMAN,
A0A0C4DFL7_HUMAN
UniprotKB:
Q16850,
A0A0C4DFL7
UniParc:
UPI00001281E9,
UPI0000EE584C,
UPI000013C4D5
EMBL:
U51685,
U51687,
U51690,
U51689,
AK314205,
U51692,
U51688,
U51684,
AC000120,
U51686,
CH236949,
U23942,
CH471091,
D55653,
U51691,
BC032322,
AK295932
Ensembl:
ENSG00000001630
KO:
hsa:1595
|
| Nucleutide sequences |
EMBL-CDS:
EAW76858.1,
BAG58717.1,
BAG36881.1,
AAB39951.1,
AAB46356.1,
EAW76859.1,
EAL24154.1,
AAC50951.1,
AAH32322.1,
BAA09512.1
Ensembl_TRS:
ENST00000450723,
ENST00000003100
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000406757,
ENSP00000003100
RefSeq:
NP_001139624.1,
NP_000777.1
|
| Others |
UniRef100:
UniRef100_Q16850
UniRef90:
UniRef90_Q16850
UniRef50:
UniRef50_Q64654
UniGene:
Hs.417077
CCDS:
CCDS55123.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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