| Type | Description |
|---|---|
| Definition | immunity-related GTPase family M member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:27:00 | Irgm1 knockout indirectly inhibits regeneration after skeletal muscle injury in mice. | 32311672 |
| 2020-07-25 12:12:00 | These studies reveal a novel role for Irgm1 in host defense and suggest that deficiencies in survival and remodeling of C-LP myeloid cells that control inflammatory intestinal bacteria may underpin IBD pathogenesis linked to IRGM dysfunction. | 32453761 |
| 2019-06-15 13:01:00 | verify that immune-responsive gene 1 (IRG1) is up-regulated in the absence of A20 and that its levels are transcriptionally regulated. | 29733654 |
| 2019-06-01 11:06:00 | IRGM inhibits NLRP3 inflammasome activation to keep colonic inflammation under check. | 30612879 |
| 2018-10-06 12:24:00 | This work establishes the importance of Irgm1(-/-) mice as a model to elucidate host-environment interactions that regulate mucosal homeostasis and intestinal inflammatory responses. | 29361512 |
| Type | IDs |
|---|---|
| Synonymous | Ifggd3, Ifi1, Iigp3, Iipg3, Irgm |
| Gene |
UniProtKB-ID:
IRGM1_MOUSE,
J7NUP1_MOUSE
UniprotKB:
Q60766,
J7NUP1
UniParc:
UPI00001E593C,
UPI000002849E
EMBL:
AK002545,
BC145957,
AL645849,
AK167558,
U19119,
AK171743,
FR734034
Ensembl:
ENSMUSG00000116444,
ENSMUSG00000046879
KO:
mmu:15944
|
| Nucleutide sequences |
EMBL-CDS:
AAI45958.1,
BAE39622.1,
AAB48942.1,
BAB22176.1,
BAE42645.1,
CBY65997.1
Ensembl_TRS:
ENSMUST00000229243,
ENSMUST00000097271,
ENSMUST00000230442,
ENSMUST00000049519
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000050446,
ENSMUSP00000155118,
ENSMUSP00000094870,
ENSMUSP00000154822
RefSeq:
XP_030101456.1,
NP_032352.1,
XP_011247066.1,
NP_001342686.1
|
| Others |
UniRef100:
UniRef100_Q60766
UniRef90:
UniRef90_Q60766
UniRef50:
UniRef50_Q60766
UniGene:
Mm.29938
CCDS:
CCDS88149.1,
CCDS24588.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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