| Type | Description |
|---|---|
| Definition | immediate early response 2 |
| Date | Results | Publications |
|---|---|---|
| 2012-11-03 11:50:00 | Relief of contact inhibition was associated with translocation of the Ier2 protein from the cytoplasm to the nucleus in both 3T3 fibroblasts and 1AS tumor cells | 22120713 |
| 2010-01-21 00:00:00 | shows a rapid and long-lasting induction after cerebral ischemia; induces cell death in primary neurons and displays several hallmarks of pro-apoptotic activity upon overexpression | 14747749 |
| Type | IDs |
|---|---|
| Synonymous | AI317238, Ch1, Pip92 |
| Gene |
UniProtKB-ID:
IER2_MOUSE
UniprotKB:
P17950
UniParc:
UPI000002108C
EMBL:
BC002067,
AK170433,
M59821,
L26490,
AC145556,
AK032692,
AK144601,
M31042
Ensembl:
ENSMUSG00000053560
KO:
mmu:15936
|
| Nucleutide sequences |
EMBL-CDS:
BAC27990.1,
BAE25960.1,
AAA39931.1,
AAB00120.1,
BAE41793.1,
AAH02067.1,
AAA40059.1
Ensembl_TRS:
ENSMUST00000060427
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000060275
RefSeq:
NP_034629.3
|
| Others |
UniRef100:
UniRef100_P17950
UniRef90:
UniRef90_P17950
UniRef50:
UniRef50_P17950
UniGene:
Mm.399
CCDS:
CCDS22474.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 26238476 |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev. Biol. Jordan P Lewandowski , Fang Du , Shilu Zhang , Marian B Powell , Kristin N Falkenstein , Hongkai Ji , Steven A Vokes |
2015-10-01 |
Pkdcc,
Tecr,
Osr2,
Ap1s2,
Pmch,
Ppp2r4,
Alx4,
Apoa2,
Aprt,
Avpr2,
Prdm1,
Bmp2,
Bmp4,
Bmpr1b,
Runx3,
Cdk6,
Cntfr,
Dcn,
Dlk1,
Dlx5,
Drd3,
Ebf3,
Sparcl1,
Ednrb,
Efna1,
Eomes,
Epha3,
Foxf2,
Fzd7,
Gata5,
Gli1,
Grcc10,
Hand2,
Hccs,
Foxf1,
Hhip,
Hmga1,
Hoxa7,
Hoxb4,
Hoxc4,
Hoxd10,
Hoxd11,
Hoxd13,
Id3,
Ier2,
Ier5,
Igf1r,
Inha,
Irx3,
Isl1,
Jag1,
Kit,
Klf3,
Klf9,
Lum,
Xpnpep2,
Zfp704,
Slc8b1,
Smad7,
Meis1,
Mgmt,
Meis2,
Polr2k,
Myl4,
Nfe2l3,
Cldn11,
Pam,
Pax1,
Pax9,
Pbx1,
Enpp1,
Prkce,
Ptch1,
Ptch2,
Igdcc3,
Aldh1a2,
Mrpl23,
Sfrp2,
Shcbp1,
Slc2a1,
Ncor2,
Sox4,
Sp1,
Sall3,
Depdc7,
Pqlc2,
Tank,
Tbx2,
Tbx3,
Tbx4,
Lrrc20,
Tmem5,
Tcte3,
Stxbp6,
Tpd52l1,
Wnt11,
Cyyr1,
Xpa,
Zfp281
|
| 22120713 |
Oncogene A Neeb , S Wallbaum , N Novac , S Dukovic-Schulze , I Scholl , C Schreiber , P Schlag , J Moll , U Stein , J P Sleeman |
2012-08-16 | - |
| 22465667 |
Dev. Cell Javier Lopez-Rios , Dario Speziale , Dimitri Robay , Martina Scotti , Marco Osterwalder , Gretel Nusspaumer , Antonella Galli , Georg A Holländer , Marie Kmita , Rolf Zeller |
2012-04-17 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 16782087 |
Dev. Biol. Tomi Jukkola , Laura Lahti , Thorsten Naserke , Wolfgang Wurst , Juha Partanen |
2006-09-01 |
Etv5,
Aldh1a1,
Phox2a,
Atoh1,
Neurog2,
Ccnd2,
Ckb,
Dach1,
Ednrb,
En1,
En2,
Fgf15,
Fgf17,
Fgf18,
Fgf8,
Fgfr1,
Fst,
Gata3,
Hes3,
Slc6a4,
Ier2,
Igfbp5,
Jarid2,
Mab21l1,
Il17rd,
Ascl1,
Ngfr,
Nr4a2,
Otx2,
Pax5,
Pea15a,
Etv4,
Pitx3,
Pltp,
Sfrp2,
Slc18a3,
Sox3,
Tcf7,
Th,
Trh,
Tubb3,
Uncx,
Sox21,
Vtn,
Abcc4,
Spry1,
Spry2,
Rgma,
Fev,
Ccnb1,
Cnpy1,
Tnfrsf19,
C130071C03Rik,
D930028M14Rik,
Apcdd1,
Dusp6,
Wfdc1,
Flrt3,
Fgfbp3
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 15747579 |
DNA Res. Motoi Nishimura , Norihide Yokoi , Takashi Miki , Yukio Horikawa , Hirokazu Yoshioka , Jun Takeda , Osamu Ohara , Susumu Seino |
2004-10-31 | - |
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 15142957 |
Cereb. Cortex Nobuo Funatsu , Takayoshi Inoue , Shun Nakamura |
2004-09-01 |
Npy,
Neurog2,
Atp8a1,
Bcl6,
Cacna2d1,
Cdk1,
Cdh6,
Cdh8,
Cetn3,
Crabp1,
Crlf1,
Crym,
Cux1,
Dvl2,
Eomes,
Epha3,
Myh7,
Fn1,
hop,
Ier2,
Igfbp3,
Mef2c,
Nfe2l3,
Nfil3,
Nin,
Ntsr1,
Pax6,
Penk,
Pou3f1,
Cyth3,
Ptprk,
Rasgrp2,
Rxrg,
Scg2,
Sema7a,
Slc8a1,
Sst,
Sox5,
Tgfbr1,
Thy1,
Tle3,
Tst,
Ttr,
Wfs1,
Wnt7b,
Tgif2,
Txnrd3,
Sowaha,
Mmp17,
Map2k6,
Lsamp,
Jade1,
Vsnl1,
Negr1,
Ngef,
Htra1,
Fam60a,
Fxyd7,
Nrgn,
Osbpl1a,
1810009A15Rik,
Dusp6,
Rab3b,
Hopx,
Limch1,
Nav2,
Gmip,
Tiparp
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员