| Type | Description |
|---|---|
| Definition | iduronidase, alpha-L |
| Date | Results | Publications |
|---|---|---|
| 2016-07-02 10:47:00 | This study demonstrated that the distribuation of bis(monoacylglycero)phosphate in brain of mucopolysaccharidosis 1 (Hurler) mouse. | 26710715 |
| 2011-12-17 11:40:00 | Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking alpha-l-iduronidase. | 21873421 |
| 2010-05-03 11:49:00 | Studies show that mouse Idua-W392X mutation is analogous to the human IDUA-W402X mutation commonly found in MPS I-H patients. | 19751987 |
| 2010-01-21 12:36:00 | Data show that late-stage erythroid cells, transduced with a tissue-specific lentiviral vector, can deliver alpha-L-iduronidase continuously and can correct the disease phenotype in both viscera and CNS of MPS I mice. | 19903883 |
| 2010-01-21 00:00:00 | IDUA(-/-) mice from adolescence to maturity, exhibited locomotor and anxiety-like compulsive behaviors, spatial learning and memory, visual recognition and short-term non-associative memory retention. | 18022143 |
| Type | IDs |
|---|---|
| Synonymous | 6030426D08 |
| Gene |
UniProtKB-ID:
Q8BLF6_MOUSE,
Q3U1Z0_MOUSE,
Q8BMG0_MOUSE
UniprotKB:
Q8BLF6,
Q3U1Z0,
Q8BMG0
UniParc:
UPI00000EB46B,
UPI00000EB332,
UPI00005ACF47
EMBL:
AC161813,
AK155627,
AK031414,
AK045330
Ensembl:
ENSMUSG00000033540
KO:
mmu:15932
|
| Nucleutide sequences |
EMBL-CDS:
BAC32313.1,
BAE33353.1,
BAC27393.1
Ensembl_TRS:
ENSMUST00000119212,
ENSMUST00000071650,
ENSMUST00000112563
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113190,
ENSMUSP00000071577,
ENSMUSP00000108182
RefSeq:
XP_006534860.1,
NP_032351.2,
XP_036020717.1,
NP_766585.1,
XP_036020714.1,
XP_036020716.1,
XP_036020715.1
|
| Others |
UniRef100:
UniRef100_Q8BLF6,
UniRef100_Q3U1Z0,
UniRef100_P48441
UniRef90:
UniRef90_P48441,
UniRef90_Q8BLF6
UniRef50:
UniRef50_P48441
UniGene:
Mm.358608
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员