| Type | Description |
|---|---|
| Definition | iduronate 2-sulfatase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:35:00 | High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II. | 32751752 |
| 2019-02-23 13:33:00 | We also show that mucopolysaccharidosis type II patient fibroblasts harboring different mutations spanning the IDS gene exhibit perturbed FGF signaling-related markers expression. Our work opens a new venue to discover possible druggable novel key targets in mucopolysaccharidosis type II | 29648648 |
| 2013-11-16 11:15:00 | While the iduronate 2-sulfatase sp replacement results in increased enzyme secretion, the addition of the ApoB-BD allows efficient BBB transcytosis and restoration of sulphamidase activity in the brain of treated mice. | 23568409 |
| 2010-01-21 00:00:00 | Ids crossing the blood-brain barrier corrects CNS defects in MPSII mice. | 19679226 |
| 2010-01-21 00:00:00 | Iduronate-2-sulfatase (IDS) is localized in lysosomes in pancreatic islet cells and expression is regulated by glucose. IDS has a potential role in the normal pathway of lysosomal degradation of secretory peptides. | 15149955 |
| Type | IDs |
|---|---|
| Synonymous | AW214631 |
| Gene |
UniProtKB-ID:
IDS_MOUSE
UniprotKB:
Q08890
UniParc:
UPI00005EE319
EMBL:
AK166178,
L07921,
BX294168,
BN000750
Ensembl:
ENSMUSG00000035847
KO:
mmu:15931
|
| Nucleutide sequences |
EMBL-CDS:
BAE38612.1,
CAI84996.1,
AAA37880.1
Ensembl_TRS:
ENSMUST00000101509
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099046
RefSeq:
XP_030107090.1,
XP_006527908.1,
XP_030107089.1,
XP_030107091.1,
XP_030107092.1,
XP_017173883.1,
XP_006527909.1,
NP_034628.2,
XP_030107093.1,
XP_017173882.1
|
| Others |
UniRef100:
UniRef100_Q08890
UniRef90:
UniRef90_Q08890
UniRef50:
UniRef50_Q08890
UniGene:
Mm.233083
CCDS:
CCDS40996.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员