例如:"NBL1", "4681", "drought"
收藏
15926 Idh1

15926

Idh1

isocitrate dehydrogenase 1 (NADP+), soluble

protein-coding

Mus musculus

基因描述

Type Description
Definition isocitrate dehydrogenase 1 (NADP+), soluble

研究结论

Date Results Publications
2020-12-12 13:28:00 Isocitrate dehydrogenase 1 mutation enhances 24(S)-hydroxycholesterol production and alters cholesterol homeostasis in glioma. 32855525
2020-05-30 10:11:00 mutant Idh1 delays tumorigenesis and sensitizes glioma tumor cells to ER stress and apoptosis 31391185
2020-05-02 12:21:00 IDH1-alpha-ketoglutarate axis plays an important role in regulating brown adipocyte differentiation and might represent a therapeutic target for treating metabolic diseases 32035087
2020-02-22 11:00:00 ATRX deficiency, in the context of wild-type IDH1, induces genomic instability, impairs nonhomologous end-joining DNA repair, and increases sensitivity to DNA-damaging therapies. 30760578
2019-10-05 11:49:00 findings support the hypothesis that IDH1(R132H) promotes glioma development. 29719265

名称对应

Type IDs
Synonymous AI314845, AI788952, E030024J03Rik, Id-1, Idh-1, Idpc
Gene
UniProtKB-ID: IDHC_MOUSE
UniprotKB: O88844
UniParc: UPI0000022759
EMBL: CH466548, AK159173, AK151212, AK160896, AF020039, AK167158, AK149019
Ensembl: ENSMUSG00000025950
KO: mmu:15926
Nucleutide sequences
EMBL-CDS: EDL00225.1, BAE30207.1, BAE34873.1, BAE28720.1, AAD02919.1, BAE36075.1, BAE39299.1, EDL00223.1
Ensembl_TRS: ENSMUST00000097709, ENSMUST00000169032
Protein sequencees
Ensembl_PRO: ENSMUSP00000127307, ENSMUSP00000095316
RefSeq: NP_034627.3, NP_001104790.1
Others
UniRef100: UniRef100_O88844
UniRef90: UniRef90_O88844
UniRef50: UniRef50_O88844
UniGene: Mm.9925
CCDS: CCDS15016.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员