| Type | Description |
|---|---|
| Definition | islet amyloid polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 10:31:00 | During fetal development, endogenous amylin favors the birth of microglial cells in the arcuate nucleus of hypothalamus and area postrema. | 30943041 |
| 2019-12-14 10:38:00 | This study that Cu(II) ions bound to the human IAPP peptide together with H2O2, can induce formation of large amounts of IAPP dimers connected by covalent dityrosine cross-links. This cross-linking is less pronounced at low pH and for murine IAPP, likely due to less efficient Cu(II) binding. | 30737030 |
| 2018-11-03 10:10:00 | These data provide for the first time evidences for the toxic nature of oligomeric assemblies of murine amylin and its existence in wild-type, non-transgenic mice. | 29372531 |
| 2018-10-13 11:54:00 | n T2 mice, the mRNA expression of Retn showed a moderate up-regulation (fold change=8.32; p=0.0019) in the adipose tissues. Iapp expression was also significantly up-regulated (fold change=9.78; p=0.012). Moreover, a 6.36-fold up-regulation for Drd5 was observed in the adipose tissues of T2 mice | 29936463 |
| 2018-09-08 11:56:00 | Data suggest that hybrid insulin peptides (HIPs), formed in insulin-secreting-cells by fusion of insulin C-peptide fragments to peptide fragments of chromogranin A or islet amyloid polypeptide, and reactivity of CD4+-T-lymphocytes to HIPs may act as biomarkers of autoimmunity in type 1 diabetes. | 29976617 |
| Type | IDs |
|---|---|
| Synonymous | DAP |
| Gene |
UniProtKB-ID:
IAPP_MOUSE
UniprotKB:
P12968
UniParc:
UPI0000001A43
EMBL:
D31820,
BC027527,
M25389
Ensembl:
ENSMUSG00000041681
KO:
mmu:15874
|
| Nucleutide sequences |
EMBL-CDS:
AAA37874.1,
BAA22051.1,
AAH27527.1
Ensembl_TRS:
ENSMUST00000041993
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043956
RefSeq:
NP_034621.1
|
| Others |
UniRef100:
UniRef100_P12968
UniRef90:
UniRef90_P12969
UniRef50:
UniRef50_P10997
UniGene:
Mm.415
CCDS:
CCDS39694.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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