| Type | Description |
|---|---|
| Definition | cytochrome P450 family 17 subfamily A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:38:00 | A change in the steroid metabolic pathway in human testes showing deteriorated spermatogenesis. | 32151535 |
| 2021-02-27 13:52:00 | Clinical and Genetic Characteristics of 17 alpha-Hydroxylase/17, 20-Lyase Deficiency: c.985_987delTACinsAA Mutation of CYP17A1 Prevalent in the Chinese Han Population. | 33547012 |
| 2021-02-20 13:35:00 | P450 CYP17A1 Variant with a Disordered Proton Shuttle Assembly Retains Peroxo-Mediated Lyase Efficiency. | 32681807 |
| 2021-02-20 13:34:00 | Discovery of Novel Non-Steroidal 17A1 Inhibitors as Potential Prostate Cancer Agents. | 32660148 |
| 2020-11-21 13:25:00 | Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen. | 32554434 |
| Type | IDs |
|---|---|
| Synonymous | CPT7, CYP17, P450C17, S17AH |
| Gene |
UniProtKB-ID:
CP17A_HUMAN,
Q1HB44_HUMAN
UniprotKB:
P05093,
Q1HB44
UniParc:
UPI0000128309
EMBL:
CH471066,
M19489,
M14564,
EU332845,
M31148,
DQ530598,
AK289898,
M31151,
M31153,
BC062997,
M63871,
M31146,
BT020000,
AL358790,
M31149,
M31147,
M31150,
M31152,
BC063388
Ensembl:
ENSG00000148795
KO:
hsa:1586
|
| Nucleutide sequences |
EMBL-CDS:
AAA59984.1,
AAA52151.1,
AAH62997.1,
AAV38803.1,
AAH63388.1,
AAA36405.1,
AAA52140.1,
BAF82587.1,
ABF50972.1,
EAW49672.1,
ABY87534.1
Gene_ORFName:
hCG_22577
Ensembl_TRS:
ENST00000369887
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358903
RefSeq:
NP_000093.1
|
| Others |
UniRef100:
UniRef100_P05093
UniRef90:
UniRef90_P05093
UniRef50:
UniRef50_P05093
UniGene:
Hs.438016
CCDS:
CCDS7541.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员