| Type | Description |
|---|---|
| Definition | prune homolog 2 with BCH domain |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:03:00 | The programmed expression of full-length BMCC1 in human neuroblastoma cells undergoing DNA damage-induced apoptosis. | 31170959 |
| 2017-06-03 12:33:00 | E2F1 directly facilitated BMCC1 transcription. These results also suggest that BMCC1 induced by E2F1 acts as a tumor suppressor through its pro-apoptotic function, resulted in favorable prognosis of neuroblastoma. | 27453342 |
| 2015-10-31 11:00:00 | Results show prostate cancer antigen 3 (PCA3) as a dominant-negative oncogene and PRUNE2 protein as an unrecognized tumor suppressor gene in prostate cancer. | 26080435 |
| 2015-09-12 10:02:00 | BMCC1 negatively regulates phosphorylation pathway of AKT, resulted in apoptosis and the BNIP2 homology region of BMCC1 interacts with BCL2. | 25611382 |
| 2015-04-18 11:23:00 | recurrent germ line and somatic mutations in PRUNE2 were found in parathyroid carcinoma and computationally predicted to be deleterious; in addition, recurrent mutations in kinase genes related to cell migration and invasion were found. | 25387265 |
| Type | IDs |
|---|---|
| Synonymous | BMCC1, BNIPXL, C9orf65, KIAA0367 |
| Gene |
UniProtKB-ID:
PRUN2_HUMAN,
B4DSQ3_HUMAN,
A0A088AWP5_HUMAN,
B4DJW7_HUMAN,
D6RTK6_HUMAN,
Q5JUB8_HUMAN,
G8XWS8_HUMAN
UniprotKB:
Q8WUY3,
B4DSQ3,
A0A088AWP5,
B4DJW7,
D6RTK6,
Q5JUB8,
G8XWS8
UniParc:
UPI0000424DD5,
UPI0001D322FE,
UPI00017A70CB,
UPI0001612CC0,
UPI000387BE77,
UPI0001D8E7D8,
UPI00017A7725,
UPI000238D766,
UPI0001D322FF,
UPI000057A151,
UPI0001D322FD
EMBL:
AL390239,
FJ808772,
AK299857,
BC022571,
KF458927,
AB002365,
AL161626,
AY439213,
AB535152,
AB050197,
AY439214,
AK298805,
AK296269,
AL359314
Ensembl:
ENSG00000106772
KO:
hsa:158471
|
| Nucleutide sequences |
EMBL-CDS:
BAD93351.1,
AAH22571.1,
AAR15151.1,
AAR15150.1,
BAG60940.1,
BAA20822.2,
BAG61715.1,
BAG58979.1,
BAJ08045.1,
ACY78253.1
Ensembl_TRS:
ENST00000376718,
ENST00000443509,
ENST00000376717
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365908,
ENSP00000393843,
ENSP00000365907
RefSeq:
XP_005251807.1,
XP_016869846.1,
XP_016869845.1,
XP_006717047.1,
XP_016869835.1,
XP_005251803.1,
XP_011516625.1,
XP_016869847.1,
XP_016869838.1,
XP_006717049.1,
XP_006717048.1,
NP_001294976.1,
XP_016869841.1,
NP_001294978.1,
NP_056040.2,
XP_011516629.1,
XP_016869836.1,
XP_016869840.1,
NP_001294977.1,
XP_005251808.1,
XP_016869837.1,
XP_005251805.1,
XP_016869834.1,
NP_001294980.1,
XP_016869839.1,
XP_016869842.1,
XP_011516628.1,
XP_016869843.1,
XP_006717046.1,
XP_005251811.1,
XP_011516630.1,
XP_005251802.1,
NP_001317609.1,
XP_016869848.1,
NP_001294979.1,
XP_006717045.1
|
| Others |
UniRef100:
UniRef100_B4DSQ3,
UniRef100_B4DJW7,
UniRef100_Q5JUB8,
UniRef100_D6RTK6,
UniRef100_G8XWS8,
UniRef100_A0A088AWP5,
UniRef100_Q8WUY3
UniRef90:
UniRef90_A0A1D5QMC1,
UniRef90_Q8WUY3-5,
UniRef90_Q8WUY3
UniRef50:
UniRef50_Q8WUY3,
UniRef50_Q8WUY3-5
UniGene:
Hs.262857
CCDS:
CCDS47982.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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