| Type | Description |
|---|---|
| Definition | cytochrome P450 family 11 subfamily B member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:07:00 | Molecular mechanisms of posaconazole- and itraconazole-induced pseudohyperaldosteronism and assessment of other systemically used azole antifungals. | 31982514 |
| 2019-06-15 10:53:00 | The study results suggest that DNA methylation at the CYP11B1 promoter plays a role in the regulation of CYP11B1 expression and cortisol production in cortisol-producing adenoma, and that somatic mutations associated with cortisol-producing adenoma reduce DNA methylation at the CYP11B1 promoter. | 28894201 |
| 2019-05-04 12:00:00 | This study reports the X-ray crystal structure of human CYP11B1 (at 2.1 A resolution) in complex with fadrozole, a racemic compound normally used to treat breast cancer by inhibiting estrogen-producing CYP19A1. | 30425102 |
| 2019-04-20 10:11:00 | Divergent gender identity was observed in three severely masculinized 46XX siblings with congenital adrenal hyperplasia who carried the same CYP11B1 mutation and had comparable postnatal and probably prenatal androgen exposure and environmental circumstances | 25100385 |
| 2019-04-13 12:21:00 | Mutation in CYP11B1 gene is associated with 11 beta-hydroxylase deficiency | 29626607 |
| Type | IDs |
|---|---|
| Synonymous | CPN1, CYP11B, FHI, P450C11 |
| Gene |
UniProtKB-ID:
C11B1_HUMAN,
Q8TDD0_HUMAN
UniprotKB:
P15538,
Q8TDD0
UniParc:
UPI000007220C,
UPI000013E0BA,
UPI000050ED65
EMBL:
AF478474,
M24667,
M32863,
EU332839,
AC083841,
M32878,
BC096286,
BC096287,
X55764,
M32879,
CH471162,
D16153,
D10169,
D16155
Ensembl:
ENSG00000160882
KO:
hsa:1584
|
| Nucleutide sequences |
EMBL-CDS:
AAH96287.1,
BAA03717.1,
CAA39290.1,
BAA01039.1,
AAH96286.1,
AAA52149.1,
ABY87528.1,
EAW82293.1,
BAB71992.1,
AAA52148.1,
AAL84813.1
Ensembl_TRS:
ENST00000517471,
ENST00000292427
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000292427,
ENSP00000428043
RefSeq:
NP_000488.3,
NP_001021384.1
|
| Others |
UniRef100:
UniRef100_Q8TDD0,
UniRef100_P15538
UniRef90:
UniRef90_P15538
UniRef50:
UniRef50_P15538
UniGene:
Hs.184927
CCDS:
CCDS6392.1,
CCDS34953.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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