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1582 CYP8B1

1582

CYP8B1

cytochrome P450 family 8 subfamily B member 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition cytochrome P450 family 8 subfamily B member 1

研究结论

Date Results Publications
2019-12-07 11:28:00 demonstration that CYP8B1 can also convert chenodeoxycholic acid (CDCA) itself to cholic acid (CA) 30465713
2014-02-22 10:09:00 RORalpha is a key regulator of diurnal rhythm and fasting induction of CYP8B1, which regulates bile acid composition and serum and liver cholesterol levels. 24226095
2013-09-28 10:41:00 The single nucleotide polymorphism rs3732860 in the 3'-untranslated region of the CYP8B1 gene is associated with risk of Gallstone Disease in Chinese Han. 23216301
2012-04-28 10:40:00 SNP rs3732860 of CYP8B1 gene is associated with gallstone disease in this Chinese population. 22093981
2010-01-21 00:00:00 T(3) dose-dependently decreased total bile acid formation in parallel with decreased expression of CYP7A1 and CYP8B1 16937432

名称对应

Type IDs
Synonymous CP8B, CYP12
Gene
UniProtKB-ID: CP8B1_HUMAN
UniprotKB: Q9UNU6
UniParc: UPI000013FCE2
EMBL: AK315330, AF090318, BC067441, AC099329, BC067444, BC067442, BC067434, AF090320
Ensembl: ENSG00000180432
KO: hsa:1582
Nucleutide sequences
EMBL-CDS: AAD19877.1, AAH67441.1, AAH67444.1, AAH67442.1, BAG37730.1, AAH67434.1, AAC63037.1
Ensembl_TRS: ENST00000316161
Protein sequencees
Ensembl_PRO: ENSP00000318867
RefSeq: NP_004382.2
Others
UniRef100: UniRef100_Q9UNU6
UniRef90: UniRef90_Q9UNU6
UniRef50: UniRef50_Q9UNU6
UniGene: Hs.447793, Hs.722743
CCDS: CCDS2707.1

全选

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研究热度

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